[go: up one dir, main page]

Murphy et al., 1981 - Google Patents

Metalloproteinases from rabbit bone culture medium degrade types IV and V collagens, laminin and fibronectin

Murphy et al., 1981

View PDF
Document ID
9986767368929291715
Author
Murphy G
Cawston T
Galloway W
Barnes M
Bunning R
Mercer E
Reynolds J
Burgeson R
Publication year
Publication venue
Biochemical Journal

External Links

Snippet

Gel-filtration chromatography of culture medium from rabbit bone explants separates three latent metalloproteinases with activities against collagen, proteoglycan and gelatin respectively. The fractions degrading proteoglycan also degrade laminin, fibronectin and the …
Continue reading at pmc.ncbi.nlm.nih.gov (PDF) (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Micro-organisms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving hydrolase

Similar Documents

Publication Publication Date Title
Murphy et al. Metalloproteinases from rabbit bone culture medium degrade types IV and V collagens, laminin and fibronectin
Stricklin et al. Human skin collagenase: isolation of precursor and active forms from both fibroblast and organ cultures
Brady et al. Recombinant expression and localization of Schistosoma mansoni cathepsin L1 support its role in the degradation of host hemoglobin
Monsky et al. Binding and localization of M r 72,000 matrix metalloproteinase at cell surface invadopodia
Goldberg Increased protease levels in transformed cells: a casein overlay assay for the detection of plasminogen activator production
Levin et al. Cultured bovine endothelial cells produce both urokinase and tissue-type plasminogen activators.
Haralson et al. Chinese hamster lung cells synthesize and confine to the cellular domain a collagen composed solely of B chains.
Sreenath et al. Expression of matrix metalloproteinase genes in transformed rat cell lines of high and low metastatic potential
Wilson et al. Molecular species of plasminogen activators secreted by normal and neoplastic human cells
Frey et al. The biosynthetic precursor of epidermal growth factor and the mechanism of its processing.
Murphy et al. Purification and characterization of a bone metalloproteinase that degrades gelatin and types IV and V collagen
Van Mourik et al. Purification of an inhibitor of plasminogen activator (antiactivator) synthesized by endothelial cells.
Davies et al. The purification and characterization of a glomerular-basement-membrane-degrading neutral proteinase from rat mesangial cells
Zucker et al. Enrichment of collagen and gelatin degrading activities in the plasma membranes of human cancer cells
Notides et al. The action of a human uterine protease on the estrogen receptor
Yamaguchi et al. Characterization of a cathepsin L-like enzyme secreted from human pancreatic cancer cell line HPC-YP
ES8607262A1 (en) ESTERS OF AMINO ACIDS AND CHROMOGEN PEPTIDES
US4889808A (en) Method of enchancing t-PA and SCU-PA production
Bózner et al. Degradation of collagen types I, III, IV and V by extracellular proteinases of an oral flagellate Trichomonas tenax
Smith et al. The evolution of proteinase substrates with special reference to dipeptidylpeptidase IV
El-Dorry et al. Dipeptidyl carboxypeptidase from seminal fluid resembles the pulmonary rather than the testicular isoenzyme
Beranger et al. Presence of gelatinase A and etalloelastase type protease at the plasma membrane of human skin fibroblasts. Influence of cytokines and growth factors on cell‐associated metalloendopeptidase levels
Berman et al. Latent collagenase in the ulcerating rabbit cornea
McDonald et al. Purification and characterization of procathepsin L, a self-processing zymogen of guinea pig spermatozoa that acts on a cathepsin D assay substrate
Kortt et al. Activities and partial purification of extracellular proteases of Bacteroides nodosus from virulent and benign footrot