[go: up one dir, main page]

Lee, 2020 - Google Patents

Sesamolin promotes cytolysis and migration activity of natural killer cells via dendritic cells

Lee, 2020

Document ID
9485603364557110467
Author
Lee J
Publication year
Publication venue
Archives of Pharmacal Research

External Links

Snippet

The defense mechanism of the immune system is based on the interaction of many kinds of leukocytes. Among them, dendritic cells (DCs) control most immune responses. In our previous study, sesamolin was shown to create an optimal environment for natural killer …
Continue reading at link.springer.com (other versions)

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2026—IL-4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant

Similar Documents

Publication Publication Date Title
McKenna et al. Plasmacytoid dendritic cells: linking innate and adaptive immunity
Wang et al. Interferon-α directly represses megakaryopoiesis by inhibiting thrombopoietin-induced signaling through induction of SOCS-1
Dunne et al. Selective expansion and partial activation of human NK cells and NK receptor-positive T cells by IL-2 and IL-15
Smyth et al. Differential tumor surveillance by natural killer (NK) and NKT cells
Walzer et al. Natural-killer cells and dendritic cells:“l'union fait la force”
Xu et al. Efficacy and mechanism-of-action of a novel superagonist interleukin-15: interleukin-15 receptor αSu/Fc fusion complex in syngeneic murine models of multiple myeloma
Romee et al. Utilizing cytokines to function‐enable human NK cells for the immunotherapy of cancer
Anguille et al. Interleukin-15 dendritic cells harness NK cell cytotoxic effector function in a contact-and IL-15-dependent manner
Maghazachi et al. CC chemokines induce the generation of killer cells from CD56+ cells
Chevalier et al. CXCR5 expressing human central memory CD4 T cells and their relevance for humoral immune responses
Morandi et al. NK cells of human secondary lymphoid tissues enhance T cell polarization via IFN‐γ secretion
Padovan et al. IFN-α2a induces IP-10/CXCL10 and MIG/CXCL9 production in monocyte-derived dendritic cells and enhances their capacity to attract and stimulate CD8+ effector T cells
Colonna et al. Interferon-producing cells: on the front line in immune responses against pathogens
Vojdani et al. Low natural killer cell cytotoxic activity in autism: the role of glutathione, IL-2 and IL-15
Liu et al. IL‐27 enhances the survival of tumor antigen‐specific CD8+ T cells and programs them into IL‐10‐producing, memory precursor‐like effector cells
Chang et al. Soypeptide lunasin in cytokine immunotherapy for lymphoma
Goodier et al. Lipopolysaccharide stimulates the proliferation of human CD56+ CD3− NK cells: a regulatory role of monocytes and IL-10
Zhang et al. Mobilization of dendritic cell precursors into the circulation by administration of MIP-1α in mice
Mirjačić Martinović et al. Favorable in vitro effects of combined IL-12 and IL-18 treatment on NK cell cytotoxicity and CD25 receptor expression in metastatic melanoma patients
Ferlazzo et al. Dendritic cell interactions with NK cells from different tissues
Lee Sesamolin promotes cytolysis and migration activity of natural killer cells via dendritic cells
Frutoso et al. Emergence of NK cell hyporesponsiveness after two IL-15 stimulation cycles
Flores et al. IL‐Y, a synthetic member of the IL‐12 cytokine family, suppresses the development of type 1 diabetes in NOD mice
Lee et al. Tissue resident Foxp3+ regulatory T cells: Sentinels and saboteurs in health and disease
Persson et al. Plasmacytoid dendritic cell‐induced migration and activation of NK cells in vivo