[go: up one dir, main page]

Bowers et al., 1962 - Google Patents

Steroids. CLXXXVII. 1 Transannular Reactions at Saturated Carbon Atoms. Part 2.2 C-19 Oxygenation3

Bowers et al., 1962

Document ID
9384700324035556145
Author
Bowers A
Denot E
Ibáñez L
Cabezas M
Ringold H
Publication year
Publication venue
The Journal of Organic Chemistry

External Links

Snippet

The importance of C-19 oxygenated steroids is discussed. Androstane-3/3, 6/3, 17/3-triol 3, 17-diacetate (Xa) readilyformed the 6/3, 19-oxide Xlla upon treatment with lead tetraacetate in benzene solution. Oxidation of the oxide Xlla with chromium trioxide led to the lactone XIa …
Continue reading at pubs.acs.org (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/0037—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton

Similar Documents

Publication Publication Date Title
Mazur et al. The Synthesis of the Steroidal Sapogenins1, 2
Engel et al. Steroids and related products. XXIII. Cardiotonic steroids. I. The synthesis of 14β-hydroxy cardenolides. Part I
US3262949A (en) 7-methyl androstane compounds
Wendler et al. The Faworskii rearrangement in the formation of 17-methyl steroids: The configuration of C-17 bromides
Beyler et al. Bismethylenedioxy Steroids. III. The Synthesis of 7α-and 7β-Methylhydrocortisones1
Berkoz et al. Steroids CCXXX. Conversion of 6β, 19-oxides and lactones into 19-nor steroids
US3170934A (en) Unsaturated 19-oxygenated 3-oxosteroids and process for their manufacture
Bowers et al. Steroids. CLXXXVII. 1 Transannular Reactions at Saturated Carbon Atoms. Part 2.2 C-19 Oxygenation3
Georgian et al. The transformation of d-homosteroids to steroids: A stereospecific benzilic acid rearrangement
Halpern et al. Steroids. CCLXVI. 1 A Series of C-19 Modified Analogs of Testosterone and Related Compounds2
US3515719A (en) 7-methyl-6,19-epoxy steroids of the androstane series
US3356677A (en) 1alpha, 2alpha-and 6alpha, 7alpha-dihalomethylene androstenes
Dugan et al. Terpenoids: V. Senegenin: Functional Groups and Part Structure
ZDERIC et al. Steroids. CLXXXI. 1 11a-Aza-and 11a-Oxa-C-homo Steroidal Hormone Analogs
US3254098A (en) Process for the production of 19 norandrostanes and 19 nor-pregnanes
Sollman Oxidation of 6β-Hydroxy-3α, 5α-cycloandrostan-17-one with Lead Tetraacetate. A Route to 19-Norsteroids from i-Steroids
Casanova et al. 593. Steroids. Part V. Partial synthesis of 9: 11-anhydrocorticosterone acetate [21-acetoxypregna-4: 9 (11)-diene-3: 20-dione]
US3787394A (en) 19-nor-7alpha-methyl or 19-nor-20-spirox-4,14-dien-3-one and 18-methyl derivatives thereof
US3178414A (en) 18-substituted steroids and process for their manufacture
Clinton et al. D-Homosteroids. III. The Synthesis of D-Homocortisone Acetate and Related Compounds1
US3080381A (en) Optionally 6-methylated and optionally 17-alkanoyloxygenated 2-oxapregnane-3, 20-diones, a-homo compounds corresponding, and 4, 5-dehydro and 4, 5; 6, 7-bisdehydro derivatives thereof
US3405127A (en) 12, 17-dioxygenated steroids
US3014936A (en) 15-dehydro-cortical hormones
Taub et al. Transformations in the 16-Acetyl-5β-androstane Series
Djerassi et al. Experiments in the Hecogenin Series. 1a Part 5.1 b 22a, 5β-Spirostan-3α-ol-12-one