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Gdovin et al., 1992 - Google Patents

Molecular mechanisms of visna virus Tat: identification of the targets for transcriptional activation and evidence for a post-transcriptional effect

Gdovin et al., 1992

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Document ID
9283505187270948893
Author
Gdovin S
Clements J
Publication year
Publication venue
Virology

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Visna virus is a pathogenic lentivirus of sheep that is distantly related to the primate lentiviruses, including the human immunodeficiency virus type 1 (HIV-1). Replication of HIV- 1 in cell culture requires the expression of a virus-encoded protein, Tat, which is a potent …
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • C12N2740/00—Reverse Transcribing RNA Viruses
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    • C12N2740/10011—Retroviridae
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    • C12N2740/10011—Retroviridae
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