Chantler et al., 1992 - Google Patents
Quantification of the in vitro activity of some compounds with spermicidal activityChantler et al., 1992
- Document ID
- 9005490793696268790
- Author
- Chantler E
- Fisher H
- Solanki S
- Elstein M
- Publication year
- Publication venue
- Contraception
External Links
Snippet
The in vitro spermicidal activity of the commonly used surfactant spermicides and the antiseptic chlorhexidine, were quantified in a statistically reproducible manner, using donor semen and image capture analysis. The spermicidal activity was expressed as the ED 50 …
- 230000001150 spermicidal 0 title abstract description 41
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane, progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N-C(=NH)-NH2), isourea (N=C(OH)-NH2), isothiourea (-N=C(SH)-NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S514/00—Drug, bio-affecting and body treating compositions
- Y10S514/931—Veneral disease
- Y10S514/934—Virus
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Waller et al. | In vitro spermicidal activity of gossypol | |
Zaneveld et al. | Efficacy and safety of a new vaginal contraceptive antimicrobial formulation containing high molecular weight poly (sodium 4-styrenesulfonate) | |
US5545401A (en) | Antiviral, spermicidal vaginal gel and foam containing low molecular weight povidone-iodine | |
Linder et al. | Effect of acute exposure to boric acid on the male reproductive system of the rat | |
AU661968B2 (en) | Method for inactivating enveloped viruses and sperm | |
US8552064B2 (en) | Suramin and derivatives thereof as topical microbicide and contraceptive | |
AU2007229268B2 (en) | Contraceptive composition | |
JPH10507178A (en) | Use and composition of anti-sexually transmitted disease preparations | |
Moench et al. | Microbicide excipients can greatly increase susceptibility to genital herpes transmission in the mouse | |
Chantler et al. | Quantification of the in vitro activity of some compounds with spermicidal activity | |
US4602042A (en) | Contraceptive methods | |
Bao-Liang et al. | In vitro spermicidal activity of parabens against human spermatozoa | |
Shimizu et al. | Progesterone-evoked increases in sperm [Ca2+] i correlate with the egg penetrating ability of sperm from fertile but not infertile men | |
Stratton et al. | Prevention of sexually transmitted infections: physical and chemical barrier methods | |
D’Cruz et al. | GM-144, a novel lipophilic vaginal contraceptive gel-microemulsion | |
Kumar et al. | Evaluation of safety margins of Chenopodium album seed decoction: 14-day subacute toxicity and microbicidal activity studies | |
Louis et al. | A comparison of the effects of nonoxynol-9 and chlorhexidine on sperm motility | |
Courtot et al. | Contraception: Effects of cholic acid and ‘Protectaid’formulations on human sperm motility and ultrastructure | |
Ratsula et al. | Vaginal contraception with gossypol: a clinical study | |
Harrison et al. | The effect of nonoxynol-9 and chlorhexidine on HIV and sperm in vitro | |
Phillips et al. | An assay for HIV infection of cultured human cervix-derived cells | |
JP2008163047A (en) | 2,4-dichlorobenzyl alcohol and amyl metacresol against hiv infectious disease | |
Hong et al. | The inhibitory effect of gossypol on human sperm motility: relationship with time, temperature and concentration | |
Turner | Recent observations on drugs and human fertility | |
US7144921B2 (en) | Composition having antibacterial and antifungal properties |