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Davis et al., 1997 - Google Patents

Ziprasidone

Davis et al., 1997

Document ID
8999789094403532667
Author
Davis R
Markham A
Publication year
Publication venue
CNS drugs

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Snippet

Summary▴ Ziprasidone is a novel antipsychotic drug. It has high affinity for serotonin 5-HT 2 and dopamine D 2 receptors in vitro, with an 11-fold higher affinity for 5-HT 2 than for D 2 receptors, suggestive of a low potential for inducing motor disturbance [including …
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

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