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Willmann et al., 2013 - Google Patents

To clone or not to clone? Induced pluripotent stem cells can be generated in bulk culture

Willmann et al., 2013

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Document ID
8991339873540682246
Author
Willmann C
Hemeda H
Pieper L
Lenz M
Qin J
Joussen S
Sontag S
Wanek P
Denecke B
Schüler H
Zenke M
Wagner W
Publication year
Publication venue
PLoS One

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Induced pluripotent stem cells (iPSCs) are usually clonally derived. The selection of fully reprogrammed cells generally involves picking of individual colonies with morphology similar to embryonic stem cells (ESCs). Given that fully reprogrammed cells are highly …
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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