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Thomas et al., 2015 - Google Patents

Reprogramming LCLs to iPSCs results in recovery of donor-specific gene expression signature

Thomas et al., 2015

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Document ID
8662365933986323817
Author
Thomas S
Kagan C
Pavlovic B
Burnett J
Patterson K
Pritchard J
Gilad Y
Publication year
Publication venue
PLoS genetics

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Renewable in vitro cell cultures, such as lymphoblastoid cell lines (LCLs), have facilitated studies that contributed to our understanding of genetic influence on human traits. However, the degree to which cell lines faithfully maintain differences in donor-specific phenotypes is …
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