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Álvarez et al., 2012 - Google Patents

Sirtuin 1 is a key regulator of the IL-12 p70/IL-23 balance in human dendritic cells (DC)

Álvarez et al., 2012

Document ID
8473402363365006087
Author
Álvarez Y
Rodríguez Peña M
Municio C
Hugo E
Alonso S
Ibarrola N
Fernández N
Sánchez Crespo M
Publication year

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Snippet

Stimulation of DC with the fungal surrogate zymosan produces IL-23 and a low amount of IL- 12 p70. Trans-repression of il12a transcription, which encodes IL-12 p35 chain, by proteins of the Notch family and lysine deacetylation reactions have been reported as the underlying …
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