[go: up one dir, main page]

Garstecki et al., 2006 - Google Patents

Mixing with bubbles: a practical technology for use with portable microfluidic devices

Garstecki et al., 2006

View PDF
Document ID
8383903516377139168
Author
Garstecki P
Fuerstman M
Fischbach M
Sia S
Whitesides G
Publication year
Publication venue
Lab on a Chip

External Links

Snippet

This paper demonstrates a methodology for micromixing that is sufficiently simple that it can be used in portable microfluidic devices. It illustrates the use of the micromixer by incorporating it into an elementary, portable microfluidic system that includes sample …
Continue reading at projects.iq.harvard.edu (PDF) (other versions)

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated micro-fluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated micro-fluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F13/00Other mixers; Mixing plant, including combinations of mixers, e.g. of dissimilar mixers
    • B01F13/0059Micromixers
    • B01F13/0061Micromixers using specific means for arranging the streams to be mixed
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F5/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F5/04Injector mixers, i.e. one or more components being added to a flowing main component
    • B01F5/0403Mixing conduits or tubes, i.e. conduits or tubes through which the main component is flown
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F5/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F5/06Mixers in which the components are pressed together through slits, orifices, or screens; Static mixers; Mixers of the fractal type
    • B01F5/0602Static mixers, i.e. mixers in which the mixing is effected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F5/0609Mixing tubes, e.g. the material being submitted to a substantially radial movement or to a movement partially in reverse direction
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F3/00Mixing, e.g. dispersing, emulsifying, according to the phases to be mixed
    • B01F3/08Mixing, e.g. dispersing, emulsifying, according to the phases to be mixed liquids with liquids; Emulsifying
    • B01F3/0807Emulsifying
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F15/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F15/02Feed or discharge mechanisms
    • B01F15/0201Feed mechanisms
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F2215/00Auxiliary or complementary information in relation with mixing
    • B01F2215/04Technical information in relation with mixing
    • B01F2215/0413Numerical information
    • B01F2215/0418Geometrical information
    • B01F2215/0431Numerical size values, e.g. diameter of a hole or conduit, area, volume, length, width, or ratios thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F2215/00Auxiliary or complementary information in relation with mixing
    • B01F2215/0001Field of application of the mixing device

Similar Documents

Publication Publication Date Title
Garstecki et al. Mixing with bubbles: a practical technology for use with portable microfluidic devices
Tice et al. Formation of droplets and mixing in multiphase microfluidics at low values of the Reynolds and the capillary numbers
US6454945B1 (en) Microfabricated devices and methods
Lee et al. The hydrodynamic focusing effect inside rectangular microchannels
US6705357B2 (en) Method and apparatus for gradient generation
Mensing et al. An externally driven magnetic microstirrer
Bhagat et al. Enhancing particle dispersion in a passive planar micromixer using rectangular obstacles
Hosokawa et al. Droplet-based nano/picoliter mixer using hydrophobic microcapillary vent
Burke et al. Stopped-flow enzyme assays on a chip using a microfabricated mixer
US20020150502A1 (en) Surface tension reduction channel
Stehle et al. Small-angle X-ray scattering in droplet-based microfluidics
Tabeling A brief introduction to slippage, droplets and mixing in microfluidic systems
KR100941069B1 (en) Microfluidic dilution device
US9194780B2 (en) Microfluidic passive mixing chip
Shin et al. Centrifuge-based step emulsification device for simple and fast generation of monodisperse picoliter droplets
JP3974531B2 (en) Microchannel mixing method and microchannel apparatus
US11141730B2 (en) Coalescence of droplets
US20080080302A1 (en) Droplet mixing method and apparatus
Weigl et al. Whole blood diagnostics in standard gravity and microgravity by use of microfluidic structures (T-sensors)
Nichols et al. Recirculating, passive micromixer with a novel sawtooth structure
Chang et al. Fabrication of the PDMS microchip for serially diluting sample with buffer
CN106378217B (en) The micro-fluidic chip of profit oil and two kinds of drops of water profit can be generated
JP2008014791A (en) Liquid mixing device, liquid mixing method, and trace analyte measurement method
Naher et al. An overview of microfluidic mixing application
Greiner et al. Design analysis and 3D measurement of diffusive broadening in a Y-mixer