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Rossbach, 2010 - Google Patents

Small non-coding RNAs as novel therapeutics

Rossbach, 2010

Document ID
823805490913394719
Author
Rossbach M
Publication year
Publication venue
Current molecular medicine

External Links

Snippet

RNA interference (RNAi), an evolutionarily conserved sequence-specific post-transcriptional gene silencing mechanism, is triggered by double-stranded RNA (dsRNA) that results in the degradation of homologous mRNA or in the inhibition of mRNA translation. The naturally …
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
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