[go: up one dir, main page]

Charon et al., 1985 - Google Patents

Chemical synthesis and immunological activities of glycolipids structurally related to lipid A

Charon et al., 1985

Document ID
8136047206550381973
Author
Charon D
Chaby R
Malinvaud A
Mondange M
Szabo L
Publication year
Publication venue
Biochemistry

External Links

Snippet

Complete chemical syntheses of a number of monosaccharides derived from 2-deoxy-2- [(3/?)-3-hydroxytetradecanamido]-D-glucopyranose and structurally related to the hydrophobic moiety (lipid A) of several bacterial endotoxins are described. Selected …
Continue reading at pubs.acs.org (other versions)

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06Fatty acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P-C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids

Similar Documents

Publication Publication Date Title
Charon et al. Chemical synthesis and immunological activities of glycolipids structurally related to lipid A
EP1232168B1 (en) Synthetic lipid-a analogs and uses thereof
RU2095366C1 (en) Compound, pharmaceutically acceptable salt thereof, and pharmaceutical composition
US5158939A (en) Method of stimulating the immune systems of animals and compositions useful therefor
CA2626997C (en) Analogs of alpha galactosylceramide and uses thereof
AU690358B2 (en) Dicarboxymethylated glycolipid derivatives as cell adhesion inhibitors
CA2344652C (en) Carboxymethylgalactose derivatives
JPS6356239B2 (en)
PL110353B1 (en) Method of producing new derivatives of glucosoamine
HUT70404A (en) SULFATED BéTA-GLYCOLIPID DERIVATIVES AS CELL ADHESION INHIBITORS AND PHARMACEUTICAL COMPNS. CONTG. THEM
US20130035479A1 (en) Functionalized beta 1,6 glucosamine disaccharides and process for their preparation
EP0080442B1 (en) Process for the preparation of di-galactose derivatives
EP0642523B1 (en) Ganglioside analogs
US5220008A (en) Oligosaccharide inhibitors for influenza virus
US5254676A (en) Oligosaccharide inhibitors for influenza virus
US5352811A (en) Method of preparing alkanoyloxytetrodecanoic acid by assymmetric allylboratron
EP0643718A1 (en) IMMUNOSUPPRESSIVE AND TOLEROGENIC MODIFIED LEWIS?C AND LacNAc COMPOUNDS
US5380829A (en) Thioglycoside analogs of gangliosides
US5830872A (en) Esters of D-mannose or of xylitol and their use as medicaments
Mochizuki et al. Lipid A-type pyrancarboxylic acid derivatives, their synthesis and their biological activities
Kamio et al. Galactosylceramide containing omega-amino-fatty acids: preparation, characterization, and sulfotransferase acceptor.
AU1858697A (en) Methods of synthesizing gm2
JP2001509777A (en) Preparation of glucosaminylmuramic acid derivative
Lewicky Synthesis of novel Lipid A analogs as potential ligands for toll-like receptor 4
WO1999010359A2 (en) Liposomic based sialyl lewis x mimetics