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Golmohammadi et al., 2024 - Google Patents

Neuroprotective effects of riluzole in Alzheimer's disease: A comprehensive review

Golmohammadi et al., 2024

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Document ID
7990796860607267538
Author
Golmohammadi M
Mahmoudian M
Hasan E
Alshahrani S
Romero‐Parra R
Malviya J
Hjazi A
Najm M
Almulla A
Zamanian M
Kadkhodaei M
Mousavi N
Publication year
Publication venue
Fundamental & Clinical Pharmacology

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Background Despite several hundred clinical trials of drugs that initially showed promise, there has been limited clinical improvement in Alzheimer's disease (AD). This may be attributed to the existence of at least 25 abnormal cellular pathways that underlie the …
Continue reading at www.researchgate.net (PDF) (other versions)

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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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