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Wu et al., 2021 - Google Patents

Click activated protodrugs against cancer increase the therapeutic potential of chemotherapy through local capture and activation

Wu et al., 2021

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Document ID
7328914369795546279
Author
Wu K
Yee N
Srinivasan S
Mahmoodi A
Zakharian M
Oneto J
Royzen M
Publication year
Publication venue
Chemical Science

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A desired goal of targeted cancer treatments is to achieve high tumor specificity with minimal side effects. Despite recent advances, this remains difficult to achieve in practice as most approaches rely on biomarkers or physiological differences between malignant and healthy …
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    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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