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Nagy et al., 1976 - Google Patents

Iron-requiring mutant of Escherichia coli carrying a deletion in the aroG-nadA region of the chromosome

Nagy et al., 1976

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Document ID
7226370925032866804
Author
Nagy J
Denes G
Publication year
Publication venue
Journal of Bacteriology

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A mutant of Escherichia coli K-12 carrying a deletion in the aroG-nadA region of the genome requires a high concentration of iron for growth. The strain is chromium sensitive, and in the presence of citrate lower concentrations of iron support cell growth. The deletion mutant lost …
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12R1/01Processes using micro-organisms using bacteria or actinomycetales
    • C12R1/185Escherichia
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving viable micro-organisms
    • C12Q1/025Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving viable micro-organisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
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