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Bauer et al., 2004 - Google Patents

Biosynthesis of tetrahydrofolate in plants: crystal structure of 7, 8-dihydroneopterin aldolase from Arabidopsis thaliana reveals a novel adolase class

Bauer et al., 2004

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Document ID
7099048158140473499
Author
Bauer S
Schott A
Illarionova V
Bacher A
Huber R
Fischer M
Publication year
Publication venue
Journal of molecular biology

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Snippet

Dihydroneopterin aldolase (DHNA) catalyses a retroaldol reaction yielding 6-hydroxymethyl- 7, 8-dihydropterin, a biosynthetic precursor of the vitamin, tetrahydrofolate. The enzyme is a potential target for antimicrobial and anti-parasite chemotherapy. A gene specifying a …
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