Christian, 2021 - Google Patents
Understanding the Role of Circulating and Tissue-Resident T cells in Cancer and AutoimmunityChristian, 2021
View PDF- Document ID
- 7024928174734578810
- Author
- Christian L
- Publication year
External Links
Snippet
T cells have long been regarded as essential contributors in cancer surveillance and autoimmune disease, due to their vast abilities to coordinate, execute and monitor the adaptive immune response. Although many studies have focused on the important …
- 210000001744 T-Lymphocytes 0 title abstract description 224
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material Not used, see subgroups
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Mandula et al. | Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses | |
JP2020072755A (en) | Chimeric antigen receptor (car) and production and use method of the same | |
US11946936B2 (en) | Beta-catenin inhibitors in cancer immunotherapy | |
KR20190114966A (en) | Engineered natural killer cells and uses thereof | |
JP2018516592A (en) | Methods for improving efficacy and proliferation of chimeric antigen receptor expressing cells | |
CN114222815A (en) | SUV39H1 deficient immune cells | |
US20210213058A1 (en) | Methods and compositions for use of tumor self-antigens in adoptive immunotherapy | |
ES2971659T3 (en) | Procedure for the production of a T cell composition | |
US20210015866A1 (en) | Tissue resident memory cell profiles, and uses thereof | |
Wang et al. | The dilemmas and possible solutions for CAR-T cell therapy application in solid tumors | |
KR20230024283A (en) | Methods for identifying features associated with clinical response and uses thereof | |
JP2022545467A (en) | Combination therapy of T cell therapy with zeste homolog 2 enhancer (EZH2) inhibitors and related methods | |
JP2021534752A (en) | Immunotherapy targeting KRAS or HER2 antigens | |
US11215618B2 (en) | Articles and methods directed to personalized therapy of cancer | |
Christian | Understanding the Role of Circulating and Tissue-Resident T cells in Cancer and Autoimmunity | |
KR20240012413A (en) | Compositions and methods for treating lung cancer | |
US12111319B2 (en) | Articles and methods directed to personalized therapy of cancer | |
Sugimura | Generation of functional macrophages from human embryonic organoids | |
Shergold | A novel screen to understand preDC migration and improve recruitment to the tumour microenvironment | |
Valia | Emerging Natural Killer Cell Immunotherapy for Acute Myeloid Leukemia | |
Bujanda | Prostate Cancer: Insights into Tumor Immunosuppression | |
WO2024121426A1 (en) | Method for optimizing t cells for immuno-therapy | |
Molodtsov | Resident Memory (TRM) Cell Responses to Cancer at Sites of Frequent Metastasis | |
Creasy | Investigation Of The Functional Impact Of Anti-Pd-1 On Tumor-Infiltrating Lymphocytes (Til) And Mapping Of Tumor Genomic Features Relevant For Response To Til Therapy | |
Guillen | Understanding How T Cell Receptor Recognition and Signaling Impacts CD8+ T Cell Functional Programming |