[go: up one dir, main page]

Doi et al., 2017 - Google Patents

Chd7 collaborates with Sox2 to regulate activation of oligodendrocyte precursor cells after spinal cord injury

Doi et al., 2017

View PDF @Free from Publisher
Document ID
673795215785660720
Author
Doi T
Ogata T
Yamauchi J
Sawada Y
Tanaka S
Nagao M
Publication year
Publication venue
Journal of Neuroscience

External Links

Snippet

Oligodendrocyte precursor cells (OPCs) act as a reservoir of new oligodendrocytes (OLs) in homeostatic and pathological conditions. OPCs are activated in response to injury to generate myelinating OLs, but the underlying mechanisms remain poorly understood. Here …
Continue reading at www.jneurosci.org (PDF) (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides

Similar Documents

Publication Publication Date Title
Doi et al. Chd7 collaborates with Sox2 to regulate activation of oligodendrocyte precursor cells after spinal cord injury
Zhang et al. Id4 downstream of Notch2 maintains neural stem cell quiescence in the adult hippocampus
Chiu et al. Foxp2 regulates neuronal differentiation and neuronal subtype specification
Li et al. RAS/ERK signaling controls proneural genetic programs in cortical development and gliomagenesis
Guo et al. Canonical Wnt signaling in the oligodendroglial lineage–puzzles remain
Dorn et al. Interplay of cell–cell contacts and RhoA/MRTF‐A signaling regulates cardiomyocyte identity
Villaescusa et al. A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease
Marchetto et al. A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells
Sparmann et al. The chromodomain helicase Chd4 is required for Polycomb‐mediated inhibition of astroglial differentiation
Azim et al. Persistent Wnt/β‐catenin signaling determines dorsalization of the postnatal subventricular zone and neural stem cell specification into oligodendrocytes and glutamatergic neurons
Lang et al. Adenomatous polyposis coli regulates oligodendroglial development
Chen et al. Orchestration of neuronal differentiation and progenitor pool expansion in the developing cortex by SoxC genes
Nakamura et al. Prolyl isomerase Pin1 regulates neuronal differentiation via β-catenin
Kurtsdotter et al. SOX5/6/21 prevent oncogene-driven transformation of brain stem cells
Boda et al. Early phenotypic asymmetry of sister oligodendrocyte progenitor cells after mitosis and its modulation by aging and extrinsic factors
Fujii et al. IMP 2 regulates differentiation potentials of mouse neocortical neural precursor cells
Wang et al. Developmental cytoplasmic-to-nuclear translocation of RNA-binding protein HuR is required for adult neurogenesis
Zhang et al. The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling
Szu et al. Impact of the Olig family on neurodevelopmental disorders
Afrang et al. A critical role for miR-184 in the fate determination of oligodendrocytes
Leonard et al. The Dkk3 gene encodes a vital intracellular regulator of cell proliferation
Lee et al. ERK regulates NeuroD1-mediated neurite outgrowth via proteasomal degradation
Gracia-Diaz et al. Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders
Fang et al. The committed oligodendrocyte precursor cell, a newly‐defined intermediate progenitor cell type in oligodendroglial lineage
Bauer et al. Delta‐like 1 participates in the specification of ventral midbrain progenitor derived dopaminergic neurons