[go: up one dir, main page]

Wang et al., 2024 - Google Patents

Intelligent Size‐Switchable Iron Carbide‐Based Nanocapsules with Cascade Delivery Capacity for Hyperthermia‐Enhanced Deep Tumor Ferroptosis

Wang et al., 2024

Document ID
6695732439935141805
Author
Wang J
Fang Z
Zhao C
Sun Z
Gao S
Zhang B
Qiu D
Yang M
Sheng F
Gao S
Hou Y
Publication year
Publication venue
Advanced Materials

External Links

Snippet

The ferroptosis pathway is recognized as an essential strategy for tumor treatment. However, killing tumor cells in deep tumor regions with ferroptosis agents is still challenging because of distinct size requirements for intratumoral accumulation and deep tumor penetration …
Continue reading at advanced.onlinelibrary.wiley.com (other versions)

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation; Therapies using these preparations

Similar Documents

Publication Publication Date Title
Yi et al. An enzyme‐activatable engineered DNAzyme sensor for cell‐selective imaging of metal ions
Zhang et al. Covalent organic framework nanobowls as activatable nanosensitizers for tumor‐specific and ferroptosis‐augmented sonodynamic therapy
Wang et al. Intelligent Size‐Switchable Iron Carbide‐Based Nanocapsules with Cascade Delivery Capacity for Hyperthermia‐Enhanced Deep Tumor Ferroptosis
Guo et al. A glucose/oxygen‐exhausting nanoreactor for starvation‐and hypoxia‐activated sustainable and cascade chemo‐chemodynamic therapy
Wu et al. Mesoporous polydopamine carrying manganese carbonyl responds to tumor microenvironment for multimodal imaging‐guided cancer therapy
Liu et al. HOCl‐activated aggregation of gold nanoparticles for multimodality therapy of tumors
Zhou et al. Size switchable nanoclusters fueled by extracellular ATP for promoting deep penetration and MRI‐guided tumor photothermal therapy
Wang et al. Addressable peptide self‐assembly on the cancer cell membrane for sensitizing chemotherapy of renal cell carcinoma
Guo et al. Near‐infrared laser‐triggered nitric oxide nanogenerators for the reversal of multidrug resistance in cancer
Wang et al. An intelligent nanomachine guided by DNAzyme logic system for precise chemodynamic therapy
Li et al. Light‐triggered clustered vesicles with self‐supplied oxygen and tissue penetrability for photodynamic therapy against hypoxic tumor
Chen et al. Photoacoustic imaging guided near‐infrared photothermal therapy using highly water‐dispersible single‐walled carbon nanohorns as theranostic agents
Liang et al. Porous yolk-shell Fe/Fe3O4 nanoparticles with controlled exposure of highly active Fe (0) for cancer therapy
Yang et al. Metal–organic framework nanoparticles with near-infrared dye for multimodal imaging and guided phototherapy
Zeng et al. An activatable afterglow/MRI bimodal nanoprobe with fast response to H2S for in vivo imaging of acute hepatitis
Yang et al. GSH/pH Dual Activatable Cross‐linked and Fluorinated PEI for Cancer Gene Therapy Through Endogenous Iron De‐Hijacking and in Situ ROS Amplification
Ye et al. In situ generation of gold nanoparticles on bacteria‐derived magnetosomes for imaging‐guided starving/chemodynamic/photothermal synergistic therapy against cancer
Wang et al. NIR‐II Responsive Hollow Magnetite Nanoclusters for Targeted Magnetic Resonance Imaging‐Guided Photothermal/Chemo‐Therapy and Chemodynamic Therapy
Li et al. Programmable therapeutic nanodevices with circular amplification of H2O2 in the tumor microenvironment for synergistic cancer therapy
Deng et al. Mitochondrial‐targeted copper delivery for cuproptosis‐based synergistic cancer therapy
Guan et al. A versatile and clearable nanocarbon theranostic based on carbon dots and gadolinium metallofullerene nanocrystals
Chen et al. Magnetic hydrogel microrobots delivery system for deafness prevention
CN103550776B (en) A kind of hydrophobic drug nano-particle, its preparation method and application
Yang et al. Stimulus‐Detonated Biomimetic “Nanobomb” with Controlled Release of HSP90 Inhibitor to Disrupt Mitochondrial Function for Synergistic Gas and Photothermal Therapy
Xiong et al. Biomimetic tumor cell membrane‐encapsulated nanoparticles combine NIR‐II photothermal therapy and chemotherapy for enhanced immunotherapy in triple‐negative breast cancer