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Hosoya et al., 2005 - Google Patents

Identification of a SRC‐like tyrosine kinase gene, FRK, fused with ETV6 in a patient with acute myelogenous leukemia carrying at (6; 12)(q21; p13) translocation

Hosoya et al., 2005

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Document ID
6402076470435195344
Author
Hosoya N
Qiao Y
Hangaishi A
Wang L
Nannya Y
Sanada M
Kurokawa M
Chiba S
Hirai H
Ogawa S
Publication year
Publication venue
Genes, Chromosomes and Cancer

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Snippet

The SRC family of kinases is rarely mutated in primary human tumors. We report the identification of a SRC‐like tyrosine kinase gene, FRK (Fyn‐related kinase), fused with ETV6 in a patient with acute myelogenous leukemia carrying t (6; 12)(q21; p13). Both reciprocal …
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
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    • G01N33/574—Immunoassay; Biospecific binding assay for cancer
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