[go: up one dir, main page]

Ding et al., 2024 - Google Patents

Synergistic immune augmentation enabled by covalently conjugating TLR4 and NOD2 agonists

Ding et al., 2024

Document ID
6250076634682026886
Author
Ding D
Gao R
Lei Y
Liu J
Zhou C
Wen Y
Zhou S
Guo J
Li T
Publication year
Publication venue
European Journal of Medicinal Chemistry

External Links

Snippet

Enhancing the efficacy of subunit vaccines relies significantly on the utilization of potent adjuvants, particularly those capable of triggering multiple immune pathways. To achieve synergistic immune augmentation by Toll-like receptor 4 agonist (TLR4a) and nucleotide …
Continue reading at www.sciencedirect.com (other versions)

Similar Documents

Publication Publication Date Title
Ding et al. Synergistic immune augmentation enabled by covalently conjugating TLR4 and NOD2 agonists
Diwan et al. Enhancement of immune responses by co-delivery of a CpG oligodeoxynucleotide and tetanus toxoid in biodegradable nanospheres
Diwan et al. Dose sparing of CpG oligodeoxynucleotide vaccine adjuvants by nanoparticle delivery
AU2009241645B2 (en) Products and methods for stimulating an immune response
KR102374576B1 (en) Thermostable vaccine compositions and methods of preparing same
Correia-Neves et al. Lipoarabinomannan in active and passive protection against tuberculosis
Gray et al. Generation of potent cellular and humoral immunity against SARS-CoV-2 antigens via conjugation to a polymeric glyco-adjuvant
Huang et al. Potent antigen-adjuvant delivery system by conjugation of Mycobacterium tuberculosis Ag85B-HspX fusion protein with arabinogalactan-Poly (I: C) conjugate
EP2484375A3 (en) Vaccine composition containing synthetic adjuvant
CZ20031299A3 (en) Compound vaccine
Zhou et al. Alum adjuvant and built-in TLR7 agonist synergistically enhance anti-MUC1 immune responses for cancer vaccine
Deepe Jr et al. Vaccination with an alkaline extract of Histoplasma capsulatum packaged in glucan particles confers protective immunity in mice
Liu et al. Polysaccharide PCP-I isolated from Poria cocos enhances the immunogenicity and protection of an anthrax protective antigen-based vaccine
Gartlan et al. Sterile inflammation induced by Carbopol elicits robust adaptive immune responses in the absence of pathogen-associated molecular patterns
Bolhassani et al. Endogenous and exogenous natural adjuvants for vaccine development
Krieg CpG DNA: trigger of sepsis, mediator of protection, or both?
Nguyen et al. Th1/Th17 T cell tissue-resident immunity increases protection, but is not required in a vaccine strategy against genital infection with Chlamydia trachomatis
Weilhammer et al. Enhancement of antigen-specific CD4+ and CD8+ T cell responses using a self-assembled biologic nanolipoprotein particle vaccine
Sun et al. Multiple effects of immunostimulatory DNA on T cells and the role of type I interferons
de Velasco et al. Synthetic peptides representing T-cell epitopes act as carriers in pneumococcal polysaccharide conjugate vaccines
Cerundolo et al. Synthetic iNKT cell-agonists as vaccine adjuvants—finding the balance
Chang et al. Conjugation of PEG-hexadecane markedly increases the immunogenicity of pneumococcal polysaccharide conjugate vaccine
Hayashi et al. Additive melanoma suppression with intralesional phospholipid-conjugated TLR7 agonists and systemic IL-2
Sun et al. Conjugation reaction with 8-arm PEG markedly improves the immunogenicity of Mycobacterium tuberculosis CFP10-TB10. 4 fusion protein
Sarkar et al. Residue-specific protein-glycan conjugation strategies for the development of pharmaceutically promising glycoconjugate vaccines: A recent update