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Jacobson et al., 1998 - Google Patents

Importance of the herpes simplex VirusUL24Gene for productive ganglionic infection in mice

Jacobson et al., 1998

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Document ID
594554650388787142
Author
Jacobson J
Chen S
Cook W
Kramer M
Coen D
Publication year
Publication venue
Virology

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TheUL24gene of herpes simplex virus overlaps the viral thymidine kinase (tk) gene. Most previous studies ofUL24have examinedUL24mutants that have also containedtkand sometimes other mutations. To address the importance ofUL24for viral replication in cell …
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
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