Wang et al., 2008 - Google Patents
The diploid genome sequence of an Asian individualWang et al., 2008
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- 5679909970709103659
- Author
- Wang J
- Wang W
- Li R
- Li Y
- Tian G
- Goodman L
- Fan W
- Zhang J
- Li J
- Zhang J
- Guo Y
- Feng B
- Li H
- Lu Y
- Fang X
- Liang H
- Du Z
- Li D
- Zhao Y
- Hu Y
- Yang Z
- Zheng H
- Hellmann I
- Inouye M
- Pool J
- Yi X
- Zhao J
- Duan J
- Zhou Y
- Qin J
- Ma L
- Li G
- Yang Z
- Zhang G
- Yang B
- Yu C
- Liang F
- Li W
- Li S
- Li D
- Ni P
- Ruan J
- Li Q
- Zhu H
- Liu D
- Lu Z
- Li N
- Guo G
- Zhang J
- Ye J
- Fang L
- Hao Q
- Chen Q
- Liang Y
- Su Y
- San A
- Ping C
- Yang S
- Chen F
- Li L
- Zhou K
- Zheng H
- Ren Y
- Yang L
- Gao Y
- Yang G
- Li Z
- Feng X
- Kristiansen K
- Wong G
- Nielsen R
- Durbin R
- Bolund L
- Zhang X
- Li S
- Yang H
- Wang J
- Publication year
- Publication venue
- Nature
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Snippet
Here we present the first diploid genome sequence of an Asian individual. The genome was sequenced to 36-fold average coverage using massively parallel sequencing technology. We aligned the short reads onto the NCBI human reference genome to 99.97% coverage …
- 241000282414 Homo sapiens 0 abstract description 20
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Hybridisation probes
- C12Q1/6883—Hybridisation probes for diseases caused by alterations of genetic material
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- G—PHYSICS
- G06—COMPUTING; CALCULATING; COUNTING
- G06F—ELECTRICAL DIGITAL DATA PROCESSING
- G06F19/00—Digital computing or data processing equipment or methods, specially adapted for specific applications
- G06F19/10—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
- G06F19/22—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for sequence comparison involving nucleotides or amino acids, e.g. homology search, motif or SNP [Single-Nucleotide Polymorphism] discovery or sequence alignment
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- G—PHYSICS
- G06—COMPUTING; CALCULATING; COUNTING
- G06F—ELECTRICAL DIGITAL DATA PROCESSING
- G06F19/00—Digital computing or data processing equipment or methods, specially adapted for specific applications
- G06F19/10—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
- G06F19/18—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for functional genomics or proteomics, e.g. genotype-phenotype associations, linkage disequilibrium, population genetics, binding site identification, mutagenesis, genotyping or genome annotation, protein-protein interactions or protein-nucleic acid interactions
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for mutation or polymorphism detection
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- G—PHYSICS
- G06—COMPUTING; CALCULATING; COUNTING
- G06F—ELECTRICAL DIGITAL DATA PROCESSING
- G06F19/00—Digital computing or data processing equipment or methods, specially adapted for specific applications
- G06F19/10—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
- G06F19/28—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for programming tools or database systems, e.g. ontologies, heterogeneous data integration, data warehousing or computing architectures
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- C12Q2600/00—Oligonucleotides characterized by their use
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
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- C12Q2600/00—Oligonucleotides characterized by their use
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