[go: up one dir, main page]

Lijinsky et al., 1993 - Google Patents

Carcinogenic effects in rats of nitrosopiperazines administered intravesically: possible implications for the use of piperazine

Lijinsky et al., 1993

Document ID
564853022192070589
Author
Lijinsky W
Kovatch R
Publication year
Publication venue
Cancer letters

External Links

Snippet

Two nitrosamines derived from nitrosation of piperazine, 1-nitrosopiperazine (NO-PIP) and 1, 4-dinitrosopiperazine (DNP), were administered to groups of twelve female F344 rats intravesically. The doses were, respectively, 40 mg and 5.2 mg twice a week for 48 and 36 …
Continue reading at www.sciencedirect.com (other versions)

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/30—Copper compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
    • A61K47/06—Organic compounds, e.g. mineral oil, petrolatum, synthetic polyolefins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Similar Documents

Publication Publication Date Title
Brown Anesthesia in fish
Lijinsky et al. Feeding tests in rats on mixtures of nitrite with secondary and tertiary amines of environmental importance
Ohr Tricaine methanesulfonate—I. pH and its effects on anesthetic potency
DE2515365C2 (en)
Taylor et al. Tumor induction in rats by feeding aminopyrine or oxytetracycline with nitrite
Lijinsky Induction of tumours in rats by feeding nitrosatable amines together with sodium nitrite
Campbell et al. Effect of thiabendazole upon the enteral and parenteral phases of trichinosis in mice
Toth Lack of tumorigenicity of sodium benzoate in mice
Hall et al. MISCELLANEOUS TESTS OF CARBON TETRACHLORID AS AN ANTHELMINTIC ¹
Lijinsky et al. Carcinogenic effects in rats of nitrosopiperazines administered intravesically: possible implications for the use of piperazine
JPS6313967B2 (en)
Öğretmen et al. Efficacy of clove oil, benzocaine, eugenol, 2-phenoxyethanol as anaesthetics on shabbout fish (Barbus grypus Heckel, 1843)
Tahira et al. The inhibitory effect of thioproline on carcinogenesis induced by N-benzylmethylamine and nitrite
Fraser et al. Myasthenia gravis in the dog
Ariens et al. Beware of formaldehyde in disguise
EP1129713A1 (en) Veterinary compositions for the treatment of parasitic diseases
Wilkinson A review of drug toxicity in the cat
Letcher et al. Evaluation of use of tiletamine/zolazepam for anesthesia of bullfrogs and leopard frogs
Reid Barbiturate poisoning in dogs
Beasley The druggist's general receipt book
US3070496A (en) Compositions and methods for treatment of bitterweed poisoning in livestock
Rush et al. THYROID STUDIES: II. Changes in the Thyroid Gland Produced by Fecal Extracts
Pollia Observations on rats with a transplantable fibrosarcoma treated with cevitamic (ascorbic) acid
Beasley The Druggist's General Receipt Book: Containing a Copious Veterinary Formulary: Numerous Recipes in Patent and Proprietary Medicines, Druggists' Nostrums, Etc.: Perfumery and Cosmetics: Beverages, Dietetic Articles, and Condiments: Trade Chemicals, Scientific Processes, and an Appendix of Useful Tables
US2892752A (en) Method of treating worms in ruminants