[go: up one dir, main page]

Herzog et al., 1953 - Google Patents

11-Oxygenated Steroids. I. Partial Syntheses of 11-Ketotestosterone and of Adrenosterone

Herzog et al., 1953

Document ID
5583191977246519793
Author
Herzog H
Jevnik M
Perlman P
Nobile A
Hershberg E
Publication year
Publication venue
Journal of the American Chemical Society

External Links

Snippet

Adrenosterone (I)(Reichstein's Substance G) is one of the “inactive” companion cortical steroids which were isolated from cortical extracts by Reichstein. 1-2 No processes have been described for its preparation other than chromic acid or alkaline cleavage of the side …
Continue reading at pubs.acs.org (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class

Similar Documents

Publication Publication Date Title
DE1618830C3 (en) 11 beta-OB-13beta-C-gona-1,3,5 (10) -trienes containing oxygen in the 3 and 17 positions and process for their preparation
Colton et al. 17-Alkyl-19-nortestosterones
Sondheimer et al. Steroids. LXVII. 1 The Decarboxylation of Unsaturated Steroidal Acids. Synthesis of 17-Epitestosterone and of 17-Methylepitestosterone2
Herzog et al. 11-Oxygenated Steroids. I. Partial Syntheses of 11-Ketotestosterone and of Adrenosterone
Stavely Molecular Rearrangements of 17-Hydroxy-pregnane Compounds1
Krubiner et al. Synthesis of 17-deoxy-17. alpha.-and 17. beta.-20-pregnynes and-20-pregnenes
Antonucci et al. Δ5, 7-Steroids. XIII. Steroidal Cyclic Ketals. II1, 2 the Preparation of Δ4, 7-Pregnadiene-3, 20-Dione and Δ4, 7-Pregnadiene-21-Ol-3, 20-Dione-Acetate
Slomp Jr et al. A Synthesis of Pregnane-3, 20-dione from Stigmasterol and Ergosterol1
DE1468035A1 (en) Process for the preparation of 19-alkyl steroids
Bernstein et al. 16-Hydroxylated Steroids. XIV. 1 16α-Hydroxy-6α-methyl-corticoids. Part I
EHRENSTEIN et al. Investigations on Steroids. XXVI. Synthesis of 19-Hydroxy-▵ 4-androstene-3, 17-dione1, 2
Bernstein et al. Steroidal Cyclic Ketals. VIII. 1▵ 4, 9 (11)-Pregnadi ene-17α, 21-diol-3, 20-dione
Mueller et al. The conversion of hecogenin and manogenin into derivatives of allopregnane-12, 20-dione
Halpern et al. Steroids. CCLXVI. 1 A Series of C-19 Modified Analogs of Testosterone and Related Compounds2
US3515719A (en) 7-methyl-6,19-epoxy steroids of the androstane series
US3135744A (en) Cycloalkenyl ethers of 17 beta-hydroxy androstanes
US3021345A (en) 16alpha, 17alpha-dihydroxypregnen-20-ones and process for preparation of same
US3254098A (en) Process for the production of 19 norandrostanes and 19 nor-pregnanes
Constantin et al. Preparation of the 3-Ethylenedioxy Derivatives of 11-Ketoprogesterone, Dehydrocorticosterone Acetate and Cortisone Acetate
Fried et al. Alkylated adrenal steroids. Dexamethasone-17 methyl ether
Romo et al. Steroids. XLI. 1 Synthesis of 11α, 17α-Dihydroxyprogesterone and of 11α, 17α, 21-Trihydroxyprogesterone, the 11-Epimer of Kendall's Compound F2
Mancera et al. Steroids. LXX. 1 Removal of the 17-Hydroxyl Group from 17α, 21-Dihydroxy-20-ketopregnane Derivatives2
EP0019247A1 (en) 16-Alpha-alkyl steroids, process for their preparation and pharmaceutical compositions containing them
Uskoković et al. A Nonphotolytic Synthesis of 10α-and 9β, 10α-Progesterone
US3040065A (en) Process for the production of 8(9)-dehydroprogesterone and 9alpha-hydroxyprogesterone