Winchell et al., 1998 - Google Patents
Mucosal and systemic antibody responses to a C4/V3 construct following DNA vaccination of rabbits via the Peyer's patchWinchell et al., 1998
View PDF- Document ID
- 5243725462395619492
- Author
- Winchell J
- Routray S
- Betts P
- Van Kruiningen H
- Silbart L
- Publication year
- Publication venue
- Journal of Infectious Diseases
External Links
Snippet
Abstract A plasmid encoding T1-SP10MN (A), a peptide derived from immunodominant regions of human immunodeficiency virus type 1 gp120, was delivered to rabbit Peyer's patches using a heliumdriven gene gun. Six weeks thereafter, 2 of 5 animals were given an …
- 230000004044 response 0 title abstract description 27
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Staats et al. | Cytokine requirements for induction of systemic and mucosal CTL after nasal immunization | |
| US6210663B1 (en) | Methods of augmenting mucosal immunity through systemic priming and mucosal boosting | |
| Okada et al. | Intranasal immunization of a DNA vaccine with IL-12-and granulocyte-macrophage colony-stimulating factor (GM-CSF)-expressing plasmids in liposomes induces strong mucosal and cell-mediated immune responses against HIV-1 antigens. | |
| Gallichan et al. | Specific secretory immune responses in the female genital tract following intranasal immunization with a recombinant adenovirus expressing glycoprotein B of herpes simplex virus | |
| CN1262665C (en) | Codon-optimized papilloma virus sequences | |
| US8182821B2 (en) | Flu vaccine admixture of mannan and flu antigen | |
| Lundholm et al. | Induction of mucosal IgA by a novel jet delivery technique for HIV-1 DNA | |
| IE922436A1 (en) | Induction of cytotoxic t-lymphocyte responses | |
| Hamajima et al. | Intranasal administration of HIV-DNA vaccine formulated with a polymer, carboxymethylcellulose, augments mucosal antibody production and cell-mediated immune response | |
| Vajdy et al. | Mucosal and systemic anti-HIV responses in rhesus macaques following combinations of intranasal and parenteral immunizations | |
| McGhee et al. | The common mucosal immune system: from basic principles to enteric vaccines with relevance for the female reproductive tract | |
| US20070026015A1 (en) | Method | |
| Winchell et al. | Mucosal and systemic antibody responses to a C4/V3 construct following DNA vaccination of rabbits via the Peyer's patch | |
| JP2004536107A (en) | Nucleic acid adjuvant | |
| WO1999008689A1 (en) | Mucosal immunization using particle-mediated delivery techniques | |
| Chin et al. | Manipulating systemic and mucosal immune responses with skin-deliverable adjuvants | |
| Ramsay et al. | Cytokine enhancement of immune responses important for immunocontraception | |
| Rafferty et al. | How can we design better vaccines to prevent HIV infection in women? | |
| Pacheco et al. | Intranasal immunization with HIV reverse transcriptase: effect of dose in the induction of helper T cell type 1 and 2 immunity | |
| US6355414B1 (en) | Immunopotentiating formulations for vaccinal use | |
| WINCHELL et al. | Mucosal immune response to an HIV C4/V3 peptide following nasal or intestinal immunization of rabbits | |
| Esquivel-Pérez et al. | Mucosal and systemic adjuvant effects of cholera toxin and Cry1Ac protoxin on the specific antibody response to HIV-1 C4/V3 peptides are different and depend on the antigen co-administered | |
| WO2008037033A1 (en) | Flu vaccine admixture of mannan and flu antigen | |
| Peter et al. | Immunogenicity of an inactivated vaccine for intravaginal application against bovine alphaherpesvirus type 5 (BoHV-5) | |
| Peter et al. | Development and use of mucosal vaccines: Potential and limitations |