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Hjelmgaard et al., 2006 - Google Patents

Copper (I) mediated cross-coupling of amino acid derived organozinc reagents with acid chlorides

Hjelmgaard et al., 2006

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Document ID
5136294926775552760
Author
Hjelmgaard T
Tanner D
Publication year
Publication venue
Organic & Biomolecular Chemistry

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This paper describes the development of a straightforward experimental protocol for copper- mediated cross-coupling of amino acid derived β-amido-alkylzinc iodides 1 and 3 with a range of acid chlorides. The present method uses CuCN· 2LiCl as the copper source and for …
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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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