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Ikegami et al., 2021 - Google Patents

MicroSEC: Sequence error filtering pipeline for formalin-fixed and paraffin-embedded samples

Ikegami et al., 2021

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Document ID
4942906241037629814
Author
Ikegami M
Kohsaka S
Hirose T
Ueno T
Kanomata N
Yamauchi H
Kobayashi H
Tanaka S
Mano H
Publication year

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The clinical sequencing of tumors is usually performed on formalin-fixed, paraffin-embedded (FFPE) samples and results in many sequencing errors. Most of these errors are detected in chimeric reads caused by single-strand DNA molecules with microhomology. Our filtering …
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