[go: up one dir, main page]

Thieleke‐Matos et al., 2016 - Google Patents

Host cell autophagy contributes to Plasmodium liver development

Thieleke‐Matos et al., 2016

View PDF
Document ID
4545697472675197467
Author
Thieleke‐Matos C
Lopes da Silva M
Cabrita‐Santos L
Portal M
Rodrigues I
Zuzarte‐Luis V
Ramalho J
Futter C
Mota M
Barral D
Seabra M
Publication year
Publication venue
Cellular microbiology

External Links

Snippet

Autophagy plays an important role in the defence against intracellular pathogens. However, some microorganisms can manipulate this host cell pathway to their advantage. In this study, we addressed the role of host cell autophagy during Plasmodium berghei liver infection. We …
Continue reading at onlinelibrary.wiley.com (PDF) (other versions)

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens

Similar Documents

Publication Publication Date Title
Thieleke‐Matos et al. Host cell autophagy contributes to Plasmodium liver development
Wacker et al. LC3‐association with the parasitophorous vacuole membrane of Plasmodium berghei liver stages follows a noncanonical autophagy pathway
Talman et al. PbGEST mediates malaria transmission to both mosquito and vertebrate host
Lopes da Silva et al. The host endocytic pathway is essential for Plasmodium berghei late liver stage development
Chong et al. The early phagosomal stage of Francisella tularensis determines optimal phagosomal escape and Francisella pathogenicity island protein expression
Baptista et al. Accumulation of Plasmodium berghei-infected red blood cells in the brain is crucial for the development of cerebral malaria in mice
Buguliskis et al. Rhomboid 4 (ROM4) affects the processing of surface adhesins and facilitates host cell invasion by Toxoplasma gondii
Voorberg-van der Wel et al. Transgenic fluorescent Plasmodium cynomolgi liver stages enable live imaging and purification of Malaria hypnozoite-forms
Vandermosten et al. Experimental malaria-associated acute respiratory distress syndrome is dependent on the parasite-host combination and coincides with normocyte invasion
Wang et al. Novel roles of dense granule protein 12 (GRA12) in Toxoplasma gondii infection
Petersen et al. Sequestration of cholesterol within the host late endocytic pathway restricts liver-stage Plasmodium development
Sato et al. Plasmodium berghei sporozoites acquire virulence and immunogenicity during mosquito hemocoel transit
Sahu et al. ZIPCO, a putative metal ion transporter, is crucial for Plasmodium liver‐stage development
Voss et al. Overexpression of Plasmodium berghei ATG8 by liver forms leads to cumulative defects in organelle dynamics and to generation of noninfectious merozoites
Wang et al. Mutational analysis of the GPI‐anchor addition sequence from the circumsporozoite protein of Plasmodium
Guevara et al. Toxoplasma gondii parasitophorous vacuole membrane-associated dense granule proteins regulate maturation of the cyst wall
Kamau et al. A focused small-molecule screen identifies 14 compounds with distinct effects on Toxoplasma gondii
Hopp et al. Deletion of the rodent malaria ortholog for falcipain-1 highlights differences between hepatic and blood stage merozoites
Gupta et al. Secreted protein with altered thrombospondin repeat (SPATR) is essential for asexual blood stages but not required for hepatocyte invasion by the malaria parasite Plasmodium berghei
Lehmann et al. A cysteine protease inhibitor of plasmodium berghei is essential for exo-erythrocytic development
Siddiqui et al. Identification of essential exported Plasmodium falciparum protein kinases in malaria‐infected red blood cells
Glushakova et al. Exploitation of a newly-identified entry pathway into the malaria parasite-infected erythrocyte to inhibit parasite egress
Hiller et al. Cytosolic peroxidases protect the lysosome of bloodstream African trypanosomes from iron-mediated membrane damage
Thieleke‐Matos et al. Host PI (3, 5) P2 activity is required for Plasmodium berghei growth during liver stage infection
Mello-Vieira et al. Plasmodium translocon component EXP2 facilitates hepatocyte invasion