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Belpomme et al., 2000 - Google Patents

Verapamil increases the survival of patients with anthracycline-resistant metastatic breast carcinoma

Belpomme et al., 2000

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Document ID
4337134338406200191
Author
Belpomme D
Gauthier S
Pujade-Lauraine E
Facchini T
Goudier M
Krakowski I
Netter-Pinon G
Frenay M
Gousset C
Marie F
Benmiloud M
Sturtz F
Publication year
Publication venue
Annals of oncology

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Background Verapamil (VER), a potent calcium channel blocker, has been found to overcome P-gp-mediated multidrug resistance (MDR) and to increase sensitivity to cytotoxic anticancer drugs in refractory myeloma and non-Hodgkin lymphorna. The value of VER for …
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    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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