Shen et al., 2001 - Google Patents
Antitumor effect of VNP20009, an attenuated Salmonella, in murine tumor modelsShen et al., 2001
View PDF- Document ID
- 4082060008927060200
- Author
- Shen S
- Chen J
- King I
- Zheng L
- Publication year
- Publication venue
- Oncology research
External Links
Snippet
It has long been known that tumor regression occasion ally occurs in patients with bacterial infections (1). An infection arising from a tumor may be the first clinical manifestation of neoplastic disease (2). Numerous clini cal reports describe patients with tumors infected by …
- 206010028980 Neoplasm 0 title abstract description 100
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Micro-organisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation; Therapies using these preparations
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—PROCESSES USING MICRO-ORGANISMS
- C12R1/00—Processes using micro-organisms
- C12R1/01—Processes using micro-organisms using bacteria or actinomycetales
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Shen et al. | Antitumor effect of VNP20009, an attenuated Salmonella, in murine tumor models | |
| EP1012232B1 (en) | Genetically modified tumor-targeted bacteria with reduced virulence | |
| US7514089B2 (en) | Genetically modified tumor-targeted bacteria with reduced virulence | |
| Bcrmudcs et al. | Tumor amplified protein expression therapy: Salmonella as a tumor-selective protein delivery vector | |
| Germanier et al. | Isolation and characterization of Gal E mutant Ty 21a of Salmonella typhi: a candidate strain for a live, oral typhoid vaccine | |
| US8916372B2 (en) | Strain of Salmonella enterica s. typhimurium, its use and a method to obtain a therapeutic vaccine vector | |
| CN114259056A (en) | Application of Lactobacillus rhamnosus in preparing food or medicine for preventing and/or treating ulcerative colitis | |
| US10314809B2 (en) | Application of derivative of clostridium ghonii | |
| Chen et al. | Oral delivery of tumor‐targeting Salmonella exhibits promising therapeutic efficacy and low toxicity | |
| KR102683896B1 (en) | Expression Vector for Secreting GM-CSF and Anticancer Recombinant Microbials Transformed thereby | |
| Van Dissel et al. | Divergent changes in antimicrobial activity after immunologic activation of mouse peritoneal macrophages. | |
| EP2424974B1 (en) | Mutants of francisella tularensis and uses thereof | |
| US7794730B2 (en) | Polyvalent attenuated live vaccine for preventing and curing vibriosis of cultivated fish | |
| Steenken Jr et al. | Vaccinating properties of avirulent dissociates of five different strains of tubercle bacilli | |
| Saltzman et al. | Patterns of hepatic and splenic colonization by an attenuated strain of Salmonella typhimurium containing the gene for human interleukin-2: a novel anti-tumor agent | |
| CN116478895B (en) | Recombinant Salmonella typhimurium genetically engineered strain HCS1, bacterial agents and their applications | |
| CN110859832A (en) | Application of myricetin in preparation of salmonella III type secretion system inhibitor | |
| ES2842748T3 (en) | Attenuated or inactivated pathogenic Escherichia coli for the treatment of urogenital cancer | |
| Jazowiecka-Rakus et al. | Antitumour activity of Salmonella typhimurium VNP20047 in B16 (F10) murine melanoma model. | |
| KR101660294B1 (en) | Novel bacterial vector system based on glmS | |
| WO2022006748A1 (en) | Genetically engineered live bacteria and methods of constructing the same | |
| Wang et al. | Bacteriolytic therapy with Clostridium ghonii for experimental solid tumors | |
| King et al. | Tumour therapy using Salmonella | |
| RU2658606C1 (en) | Streptococcus pyogenes n b-7612, the producer of the complex of biologically active compounds with immunostimulating properties | |
| KR102007455B1 (en) | Method for preparing live attenuated vaccine by irradiation and live attenuated vaccine composition prepared by the same |