Pandeya, 2005 - Google Patents
Combinatorial chemistry: A novel method in drug discovery and its applicationPandeya, 2005
View PDF- Document ID
- 3912633493828973281
- Author
- Pandeya S
- Publication year
External Links
Snippet
Combinatorial chemistry is a new technique developed in pharmaceutical industry, which involves synthesis of compounds in mass instead of a single compound, which are screened as a whole mixture for particular biological activity. Because of the rapid synthesis of …
- 238000005037 combinatorial chemistry 0 title abstract description 20
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL CHEMISTRY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL CHEMISTRY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—For creating libraries
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL CHEMISTRY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
- C40B30/00—Methods of screening libraries
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Terrett et al. | Combinatorial synthesis—the design of compound libraries and their application to drug discovery | |
Jacobs et al. | Combinatorial chemistry—applications of light-directed chemical synthesis | |
Lam | Mini-review. Application of combinatorial library methods in cancer research and drug discovery | |
Lam et al. | The “one-bead-one-compound” combinatorial library method | |
Gordon et al. | Applications of combinatorial technologies to drug discovery. 2. Combinatorial organic synthesis, library screening strategies, and future directions | |
Liu et al. | Combinatorial peptide library methods for immunobiology research | |
US5646285A (en) | Combinatorial non-peptide libraries | |
Houghten et al. | Mixture-based synthetic combinatorial libraries | |
Bunin et al. | The combinatorial synthesis and chemical and biological evaluation of a 1, 4-benzodiazepine library. | |
US5891737A (en) | Combinatorial non-peptide libraries | |
Pandeya | Combinatorial chemistry: A novel method in drug discovery and its application | |
Merritt | Solution phase combinatorial chemistry | |
An et al. | Solution phase combinatorial chemistry. Discovery of novel polyazapyridinophanes with potent antibacterial activity by a solution phase simultaneous addition of functionalities approach | |
Frank | High-density synthetic peptide microarrays: emerging tools for functional genomics and proteomics | |
Lam et al. | A one-bead one-peptide combinatorial library method for B-cell epitope mapping | |
EP0675873A1 (en) | Synthesis of encoded polymers | |
Sanchez-Martin et al. | The impact of combinatorial methodologies on medicinal chemistry | |
Maclean et al. | Glossary of terms used in combinatorial chemistry (technical report) | |
Rinnová et al. | Molecular diversity and libraries of structures: Synthesis and screening | |
Williard et al. | Combinatorial chemistry: a rational approach to chemical diversity | |
Fauchère et al. | Combinatorial chemistry for the generation of molecular diversity and the discovery of bioactive leads | |
Hlavac et al. | Practical aspects of combinatorial solid-phase synthesis | |
WO2004087933A2 (en) | A novel encoding method for 'one-bead one-compound' combinatorial libraries | |
Lam et al. | Application of “one-bead one-compound” combinatorial library methods in signal transduction research | |
WO1996030393A1 (en) | A method for the synthesis of mixtures of compounds |