[go: up one dir, main page]

Siemion et al., 1998 - Google Patents

Peptides related to FKBP 39–45 loop possess immunostimulative potency

Siemion et al., 1998

Document ID
3574701969500621618
Author
Siemion I
Strug I
Wieczorek Z
Publication year
Publication venue
Peptides

External Links

Snippet

151 Taking into account the sequential homology existing between thymopoietin II, the DNA- binding domain of p53 protein and FKBP (FK-506 binding protein), a series of fragments of human and bovine FKBP containing a fragment Ser39-Pro45 were synthesized. In the …
Continue reading at www.sciencedirect.com (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins Derivatives thereof

Similar Documents

Publication Publication Date Title
Koletsky et al. Cyclophilin: distribution and variant properties in normal and neoplastic tissues.
KR101484590B1 (en) Immunomodulator polypeptides derived from il-2 and their use thereof in the therapeutic of cancer and chronic infections
US6265535B1 (en) Peptides and peptide analogues designed from binding sites of tumor necrosis factor receptor superfamily and their uses
US6291247B1 (en) Methods of screening for factors that disrupt neurotrophin conformation and reduce neurotrophin biological activity
EP1793856A2 (en) Methods and compositions for treating allergic inflammation
KR20020062956A (en) Depsipeptide and congeners thereof for use as immunosuppressants
PT87763B (en) PROCESS FOR THE PREPARATION OF CICLIC PEPTIOLIDES
Kupper et al. Keratinocyte-derived T-cell growth factor: a T-cell growth factor functionally distinct from interleukin 2.
CA2155103A1 (en) Tnf-alpha muteins and a process for preparing them
AU694602B2 (en) Novel peptide
WO1997015593A1 (en) Neurotrophin antagonists
Cacalano et al. Evidence for a functional receptor for cyclosporin A on the surface of lymphocytes.
Deigin et al. Reciprocal effect of optical isomerism of EW-dipeptides on immune response
Cebrat et al. Immunosuppressive activity of hymenistatin I
KR20110093899A (en) Tumor Necrosis Factor Alpha Inhibitory Peptides and Uses thereof
KR101310511B1 (en) A thymus-specific protein
Siemion et al. Peptides related to FKBP 39–45 loop possess immunostimulative potency
Conlon et al. An atypical member of the brevinin-1 family of antimicrobial peptides isolated from the skin of the European frog Rana dalmatina
NO149631B (en) ANALOGY PROCEDURE FOR PREPARING BIOLOGICALLY ACTIVE POLYPEPTIDES
WO1993025580A1 (en) Cyclic peptides that modulate endothelin activity
Reem Molecular mode of action of cyclosporin and FK506in human thymocytes
Pasikowski et al. A novel immunosuppressory peptide originating from the ubiquitin sequence
Dardenne et al. Stimulatory effects of cyclosporin A on human and mouse thymic epithelial cells
EP2706113A1 (en) Synthetic peptide capable of inducing expression of type-2 tnf receptor and use thereof
Siemion et al. Anti-IL-1 activity of peptide fragments of IL-1 family proteins