Jennings et al., 1981 - Google Patents
Total ischemia in dog hearts, in vitro. 1. Comparison of high energy phosphate production, utilization, and depletion, and of adenine nucleotide catabolism in total …Jennings et al., 1981
View PDF- Document ID
- 3565968849404654019
- Author
- Jennings R
- Reimer K
- Hill M
- Mayer S
- Publication year
- Publication venue
- Circulation research
External Links
Snippet
This study was done to compare rates of high energy phosphate (HEP) utilization and depletion, as well as the production and distribution of catabolic products of adenine nucleo tides in dog heart during total ischemia in vitro and severe ischemia in vivo. Both HEP …
- 206010061255 Ischaemia 0 title abstract description 131
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharide having only carbon, hydrogen and oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Jennings et al. | Total ischemia in dog hearts, in vitro. 1. Comparison of high energy phosphate production, utilization, and depletion, and of adenine nucleotide catabolism in total ischemia in vitro vs. severe ischemia in vivo. | |
| Sparks Jr et al. | Regulation of adenosine formation by the heart. | |
| Jarmakani et al. | Effect of hypoxia on myocardial high-energy phosphates in the neonatal mammalian heart | |
| Rovetto et al. | Mechanisms of glycolytic inhibition in ischemic rat hearts. | |
| Berne et al. | Adenosine and adenine nucleotides as possible mediators of cardiac and skeletal muscle blood flow regulation | |
| Dobson Jr | Mechanism of adenosine inhibition of catecholamine-induced responses in heart. | |
| Berne | The role of adenosine in the regulation of coronary blood flow. | |
| Rubio et al. | Release of adenosine by the normal myocardium in dogs and its relationship to the regulation of coronary resistance | |
| Imai et al. | Effect of ischemia on adenine nucleotides in cardiac and skeletal muscle | |
| Reimer et al. | Total ischemia in dog hearts, in vitro 2. High energy phosphate depletion and associated defects in energy metabolism, cell volume regulation, and sarcolemmal integrity. | |
| Hansen et al. | Atlantic hagfish cardiac muscle: metabolic basis of tolerance to anoxia | |
| Karlsson et al. | Relationship between epicardial ST segment changes and myocardial metabolism during acute coronary insufficiency | |
| Bergström et al. | Muscle glycogen synthetase in normal subjects: basal values, effect of glycogen depletion by exercise and of a carbohydrate-rich diet following exercise | |
| Zimmer | Regulation of and intervention into the oxidative pentose phosphate pathway and adenine nucleotide metabolism in the heart | |
| Edlund et al. | Release of two vasodilators, adenosine and prostacyclin, from isolated rabbit hearts during controlled hypoxia. | |
| Ichihara et al. | Difference between endocardial and epicardial utilization of glycogen in the ischemic heart | |
| Snoeckx et al. | Differences in ischaemia tolerance between hypertrophied hearts of adult and aged spontaneously hypertensive rats | |
| Gaja et al. | Phosphorylation and redox states in ischemic liver | |
| Aussedat | Effect of uridine supply on glycogen resynthesis after ischaemia in the isolated perfused rat heart | |
| Becker et al. | Uric acid, the major catabolite of cardiac adenine nucleotides and adenosine, originates in the coronary endothelium | |
| Cunningham et al. | Effect of a xanthine oxidase inhibitor on adenine nucleotide degradation in hemorrhagic shock | |
| Wikström et al. | Continuous monitoring of energy metabolites using microdialysis during myocardial ischaemia in the pig | |
| Fréminet | Carbohydrate and amino acid metabolism during acute hypoxia in rats: blood and heart metabolites | |
| Chien et al. | Fructose-1, 6-diphosphate and a glucose-free solution enhances functional recovery in hypothermic heart preservation | |
| Hoskins et al. | The control of bovine sperm glycolysis during epididymal transit |