Sellin, 1985 - Google Patents
The pharmacological mechanism of botulismSellin, 1985
- Document ID
- 3442711879913196967
- Author
- Sellin L
- Publication year
- Publication venue
- Trends in Pharmacological Sciences
External Links
Snippet
In this review, Lawrence Sellin describes the botulinal neurotoxins which occur as seven immunologically distinct types A--G and may bind to a'proteoglycan component" on the extraceUular face of the nerve terminal membrane. Following binding the toxin is …
- 208000003508 Botulism 0 title description 7
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Sellin | The pharmacological mechanism of botulism | |
| Bittner et al. | Isolated light chains of botulinum neurotoxins inhibit exocytosis: studies in digitonin-permeabilized chromaffin cells | |
| Gansel et al. | Distinct sites of action of clostridial neurotoxins revealed by double-poisoning of mouse motor nerve terminals | |
| Simpson et al. | Botulinum neurotoxin type E: studies on mechanism of action and on structure-activity relationships. | |
| NO962405D0 (en) | Transdermal therapeutic system for the prevention of poisoning by phosphorus inorganic nerve toxins comprising a parasympathomimetic and a parasympatheticolytic | |
| FI961282A0 (en) | Transdermal therapeutic system with acetylsalicylic acid as active substance | |
| Hassing | Inhibition of Corynebacterium acnes lipase by tetracycline. | |
| Lange et al. | Absence of cross-tolerance to heroin in morphine-tolerant mice | |
| PT1234043E (en) | CONSTRUCTIONS FOR THE DELIVERY OF THERAPEUTIC AGENTS TO NEURONAL CELLS | |
| El-Shoura | Helicobacter pylori: I. Ultrastructural sequences of adherence, attachment, and penetration into the gastric mucosa | |
| Deshpande et al. | A study of zinc-dependent metalloendopeptidase inhibitors as pharmacological antagonists in botulinum neurotoxin poisoning | |
| Clement | Pharmacological nature of soman-induced hypothermia in mice | |
| Adler et al. | Reversal of BoNT/A-mediated inhibition of muscle paralysis by 3, 4-diaminopyridine and roscovitine in mouse phrenic nerve-hemidiaphragm preparations | |
| PT732926E (en) | PHARMACEUTICAL FORM FOR THE PROPHYLAXY OR PRE-TREATMENT OF POISONING BY ORGANOPHOSPHORUS COLINESTERASE INHIBITORS | |
| Fassio et al. | Evidence for calcium-dependent vesicular transmitter release insensitive to tetanus toxin and botulinum toxin type F | |
| Sakurai et al. | Contraction induced by Clostridium perfringens epsilon toxin in the isolated rat ileum | |
| Ilias et al. | Diltiazem inhibits halothane-induced contractions in malignant hyperthermia-susceptible muscles in vitro | |
| Epstein et al. | Toxicity of hydroxamic acid analogues; prophylactic and therapeutic efficacy against nerve gas poisoning in mice. | |
| TR199901237T2 (en) | A new therapeutic application of a thienylcyclohexylamine derivative. | |
| DE59510583D1 (en) | PHARMACEUTICAL COMPOSITION FOR SYSTEMIC TRANSDERMAL ADMINISTRATION WITH THE ACTIVE MORPHINE-6-GLUCURONIDE | |
| Simpson et al. | The role of exoproteases in governing intraneuronal metabolism of botulinum toxin | |
| Carreira et al. | Micrococcus lysodeikticus membrane ATPase. effect of trypsin on stimulation of a purified form of the enzyme and identification of its natural inhibitor | |
| López-Alonso et al. | Botulinum toxin type A inhibits Ca2+-dependent transport of acetylcholine in reconstituted giant liposomes made from presynaptic membranes from cholinergic nerve terminals | |
| Wada et al. | The effects of d-tubocurarine, hexamethonium and decamethonium on the receptor for the axon reflex sweating | |
| Poulain et al. | Botulinal neurotoxins: mode of action on neurotransmitter release |