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Saeed et al., 2023 - Google Patents

Glycol chitosan amphiphile nanotheranostic system for ultrasound-mediated localized release and biodistribution of doxorubicin

Saeed et al., 2023

Document ID
3304034848828692776
Author
Saeed S
Sarwar U
Yasinzai M
Raza A
Publication year
Publication venue
Journal of nanoparticle research

External Links

Snippet

Ultrasound-mediated delivery has garnered attention as a noninvasive modality for localized drug delivery in cancer. Doxorubicin, a chemotherapeutic drug, shows low penetration, nonspecific distribution, and uncontrolled release. We have synthesized a hydrophobic …
Continue reading at link.springer.com (other versions)

Classifications

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    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153Polyesters, e.g. poly(lactide-co-glycolide)
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    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5161Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
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    • A61K47/48861Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the conjugate being characterized by a special physical or galenical form the form being a particulate, powder, adsorbate, bead, sphere the form being an inorganic particle, e.g. a ceramic particle, silica particle, ferrite, synsorb
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