Van der Ryst et al., 1998 - Google Patents
Study of the immunogenicity of different recombinant Mengo viruses expressing HIV1 and SIV epitopesVan der Ryst et al., 1998
- Document ID
- 298728105649138649
- Author
- Van der Ryst E
- Nakasone T
- Habel A
- Venet A
- Gomard E
- Altmeyer R
- Girard M
- Borman A
- Publication year
- Publication venue
- Research in virology
External Links
Snippet
Recombinant Mengo viruses expressing heterologous genes have proven to be safe and immunogenic in both mice and primates, and to be able to induce both humoral and cellular immune responses (Altmeyer et al., 1995, 1996). Several recombinant Mengo viruses …
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- C12N2740/00—Reverse Transcribing RNA Viruses
- C12N2740/00011—Reverse Transcribing RNA Viruses
- C12N2740/10011—Retroviridae
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- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
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- C12N2740/10011—Retroviridae
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- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
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- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
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