[go: up one dir, main page]

Nalivaika, 2019 - Google Patents

Structured Conductive Probes for Mass Spectrometry

Nalivaika, 2019

View PDF
Document ID
2964424248279804221
Author
Nalivaika P
Publication year

External Links

Snippet

The introduction of ionization under ambient conditions has greatly simplified mass spectrometric analysis. Over past decade, ambient ionization mass spectrometry (MS) methods have revolutionized the way complex samples are analyzed under environmental …
Continue reading at macsphere.mcmaster.ca (PDF) (other versions)

Classifications

    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0409—Sample holders or containers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/405—Concentrating samples by adsorption or absorption
    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164—Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/165—Electrospray ionisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/90—Plate chromatography, e.g. thin layer or paper chromatography
    • G01N30/94—Development
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating the ionisation of gases; by investigating electric discharges, e.g. emission of cathode
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light

Similar Documents

Publication Publication Date Title
US11867684B2 (en) Sample dispenser including an internal standard and methods of use thereof
Mirabelli et al. Direct coupling of solid-phase microextraction with mass spectrometry: sub-pg/g sensitivity achieved using a dielectric barrier discharge ionization source
Feider et al. Ambient ionization mass spectrometry: recent developments and applications
Chipuk et al. Transmission mode desorption electrospray ionization
Van Berkel et al. Established and emerging atmospheric pressure surface sampling/ionization techniques for mass spectrometry
Ifa et al. Desorption electrospray ionization and other ambient ionization methods: current progress and preview
CA2559847C (en) Method and system for desorption electrospray ionization
Deng et al. Coupling solid-phase microextraction with ambient mass spectrometry using surface coated wooden-tip probe for rapid analysis of ultra trace perfluorinated compounds in complex samples
JP5671523B2 (en) Ion production using wet porous materials
Li et al. Rapid characterization of complex viscous samples at molecular levels by neutral desorption extractive electrospray ionization mass spectrometry
US7388195B2 (en) Apparatus and systems for processing samples for analysis via ion mobility spectrometry
Hu et al. Direct coupling of solid phase microextraction with electrospray ionization mass spectrometry: a case study for detection of ketamine in urine
CN101073137A (en) Method and system for desorption electrospray ionization
CN105074471A (en) Detection of compounds in a dried fluid spot by direct MALDI/MS
Zhang et al. Surface desorption dielectric-barrier discharge ionization mass spectrometry
JP7549644B2 (en) Molecularly encrypted sampling devices and methods of making and using same
Bianchi et al. The role of surface in desorption electrospray ionization-mass spectrometry: advances and future trends
Soparawalla et al. Pharmaceutical cleaning validation using non‐proximate large‐area desorption electrospray ionization mass spectrometry
Meher et al. Tissue paper assisted spray ionization mass spectrometry
Wang et al. Nebulization Swab Assisted Photoionization Tandem Miniaturized Ion Trap Mass Spectrometry for On-Site Analysis of Nonvolatile Compounds
Nalivaika Structured Conductive Probes for Mass Spectrometry
WO2009144560A1 (en) Method and device for sample preparation
Marcinkowska et al. Mass Spectrometry-Based Direct Analytical Techniques
Huan-Wen et al. Principle and Application of Ambient Mass Spectrometry for Direct Analysis of Complex Samples
Gómez-Ríos Strategies for the Direct Coupling of Solid Phase Microextraction to Mass Spectrometry