Li et al., 2018 - Google Patents
Regulation of Staphylococcus aureus infection of macrophages by CD44, reactive oxygen species, and acid sphingomyelinaseLi et al., 2018
View PDF- Document ID
- 2919958901678724006
- Author
- Li C
- Wu Y
- Riehle A
- Orian-Rousseau V
- Zhang Y
- Gulbins E
- Grassmé H
- Publication year
- Publication venue
- Antioxidants & redox signaling
External Links
Snippet
Aims: Staphylococcus aureus plays an important role in sepsis, pneumonia, and wound infections. Acid sphingomyelinase (Asm)-deficient mice are highly susceptible to pulmonary S. aureus infections. Here, we investigated the role of CD44 as a molecule that mediates …
- 101700078950 CD44 0 title abstract description 96
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Li et al. | Regulation of Staphylococcus aureus infection of macrophages by CD44, reactive oxygen species, and acid sphingomyelinase | |
| Zhang et al. | Toll-like receptor 5-mediated corneal epithelial inflammatory responses to Pseudomonas aeruginosa flagellin | |
| BR112017023707B1 (en) | Composition, use of a composition, recombinant vector, transgenic microorganism, and recombinant polypeptide | |
| JP6778681B2 (en) | Treatment of HMGB1-mediated inflammation | |
| US10646556B2 (en) | Methods for treatment of and prophylaxis against inflammatory disorders | |
| Meng et al. | Vimentin affects inflammation and neutrophil recruitment in airway epithelium during Streptococcus suis serotype 2 infection | |
| KR20100116612A (en) | Anti-bacterial compositions | |
| Liu et al. | Retinal Pigment Epithelial Cells Express Antimicrobial Peptide Lysozyme–A Novel Mechanism of Innate Immune Defense of the Blood-Retina Barrier | |
| US8796323B2 (en) | Defensin-like molecules as novel antimicrobial agents | |
| Zhou et al. | Desaminotyrosine is a redox‐active microbial metabolite that bolsters macrophage antimicrobial functions while attenuating IL‐6 production | |
| US9056081B2 (en) | Compositions for treating pseudomonas infection | |
| Tan | Type 1 Interferon Limits Phagocyte Antimicrobial Function by Modulating Lysosomal Cholesterol | |
| Tien | Mechanism of immune modulation in macrophages by Enterococcus faecalis | |
| Krustev | The Role of NOD1 in the Control of the Non-canonical Inflammasome | |
| Li | Regulation of Staphylococcus aureus infection of macrophages by CD44 and acid sphingomyelinase | |
| Kabus | The induction and function of the transcription factor c-myc in macrophages during pneumococcal pneumonia and legionellosis | |
| Balbirnie-Cumming | Novel macrophage microbicidal responses against gram-positive bacteria | |
| Latour | New Insights into the Regulation of the Innate Immune Response During Gastrointestinal Infection and Inflammation | |
| Cai | Modulation of Inflammasome Signaling During Chronic Bacterial Infections | |
| Myszor | Effects of aroylated phenylenediamines and mechanical stress on lung epithelial immunity | |
| WO2024163692A1 (en) | Methods for activating immune cells to kill bacteria | |
| He | Mechanism of linezolid-induced NLRP3 inflammasome activation | |
| Sigel | Innate immune recognition of Staphylococcus aureus cell wall components: Structural and functional requirements | |
| Sigel | Erkennung von Staphylococcus-aureus-Zellwandkomponenten durch das angeborene Immunsystem: strukturelle und funktionelle Voraussetzungen | |
| Farias | Interleukin 33, an inflammatory mediator in cystic fibrosis lung disease |