[go: up one dir, main page]

Meyer et al., 2020 - Google Patents

Biomolecule–polymer hybrid compartments: combining the best of both worlds

Meyer et al., 2020

View HTML
Document ID
2764523228911103453
Author
Meyer C
Abram S
Craciun I
Palivan C
Publication year
Publication venue
Physical Chemistry Chemical Physics

External Links

Snippet

Compartmentalization is a fundamental principle in biology that is needed for the temporal and spatial separation of chemically incompatible reactions and biomolecules. Nano-or micro-sized compartments made of synthetic polymers are used to mimick this principle. The …
Continue reading at pubs.rsc.org (HTML) (other versions)

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1273—Polymersomes; Liposomes with polymerisable or polymerised bilayer-forming substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
    • A61K47/48—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
    • A61K47/48769—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the conjugate being characterized by a special physical or galenical form
    • A61K47/48792—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the conjugate being characterized by a special physical or galenical form the form being a colloid, emulsion, i.e. having at least a dispersed/continuous oil phase and a dispersed/continuous aqueous phase, dispersion or suspension
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
    • A61K47/48—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
    • A61K47/48769—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the conjugate being characterized by a special physical or galenical form
    • A61K47/48853—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the conjugate being characterized by a special physical or galenical form the form being a particulate, powder, adsorbate, bead, sphere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
    • A61K47/30—Macromolecular compounds
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin, zein

Similar Documents

Publication Publication Date Title
Meyer et al. Biomolecule–polymer hybrid compartments: combining the best of both worlds
Rideau et al. Liposomes and polymersomes: a comparative review towards cell mimicking
Iqbal et al. Polymersomes for therapeutic delivery of protein and nucleic acid macromolecules: from design to therapeutic applications
Yorulmaz Avsar et al. Biomolecules turn self-assembling amphiphilic block co-polymer platforms into biomimetic interfaces
Blackman et al. Confinement of therapeutic enzymes in selectively permeable polymer vesicles by polymerization-induced self-assembly (PISA) reduces antibody binding and proteolytic susceptibility
Leong et al. Engineering polymersomes for diagnostics and therapy
Tang et al. Soft materials as biological and artificial membranes
Lussier et al. Can bottom-up synthetic biology generate advanced drug-delivery systems?
Palivan et al. Bioinspired polymer vesicles and membranes for biological and medical applications
Boyer et al. Multiple lipid compartments slow vesicle contents release in lipases and serum
Xue et al. Intracellular degradable hydrogel cubes and spheres for anti-cancer drug delivery
Tong et al. Multilayer microcapsules with tailored structures for bio-related applications
Del Mercato et al. LbL multilayer capsules: recent progress and future outlook for their use in life sciences
van Dongen et al. Biohybrid polymer capsules
Messager et al. Novel aspects of encapsulation and delivery using polymersomes
Palivan et al. Protein–polymer nanoreactors for medical applications
Xue et al. Shaped stimuli-responsive hydrogel particles: syntheses, properties and biological responses
Marguet et al. Polymersomes in “gelly” polymersomes: toward structural cell mimicry
Leggio et al. Mastering the tools: natural versus artificial vesicles in nanomedicine
Godoy-Gallardo et al. Multicompartment artificial organelles conducting enzymatic cascade reactions inside cells
Peyret et al. Liposomes in polymersomes: Multicompartment system with temperature-triggered release
Nishimura et al. Thermoresponsive polysaccharide graft polymer vesicles with tunable size and structural memory
Becker et al. Layer‐by‐layer‐assembled capsules and films for therapeutic delivery
Najer et al. Polymer nanocompartments in broad-spectrum medical applications
Lopez et al. DNA oligonucleotide-functionalized liposomes: bioconjugate chemistry, biointerfaces, and applications