[go: up one dir, main page]

Batres et al., 1956 - Google Patents

Steroids. LXXVI. Synthesis of Long Chain Carboxylic Acid Esters of 17α-Hydroxyprogesterone

Batres et al., 1956

Document ID
2473771996344117733
Author
Batres E
Gomez R
Rosenkranz G
Sondheimer F
Publication year
Publication venue
The Journal of Organic Chemistry

External Links

Snippet

Esters of 17a-hydroxyprogesterone (IV) have recently become of importance in view of the discovery that they possess long acting progestational activity in animals23 as well as in the human. 26 In contrast, free 17a-hydroxyprogesterone shows very little, if any, progestational …
Continue reading at pubs.acs.org (other versions)

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2103/00Systems containing at least three condensed rings
    • C07C2103/02Ortho- or ortho- and peri-condensed systems
    • C07C2103/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2103/22Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J63/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008Expansion of ring D by one atom, e.g. D homo steroids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J13/00Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings and containing any of the groups OH, O-metal, -CHO, keto, ether, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O-metal, -CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups

Similar Documents

Publication Publication Date Title
Fishman Synthesis of 2-Methoxyestrogens1
US2744122A (en) delta 4-19-nor-17alpha-ethinylandrosten-17beta-ol-3-one and process
Villotti et al. Steroids. CXXIII. 1 19-Nor-6-methylandrostane Derivatives
Biggerstaff et al. 3, 16β-Dihydroxy-Δ1, 3, 5-estratrien-17-one and Related Compounds1
Varma et al. Synthesis and C-25 chirality of 26-hydroxycholesterols
US2542223A (en) 6-keto-delta-10-methyldecalone-1
US2401775A (en) Alpha-substituted side-chain ketones of the cyclopentanopolyhydrophenanthrene series and process of making the same
Ringold et al. Steroids. LXXV. Dehydrogenation of testosterone to Δ1, 4-androstadien-17β-ol-3-one with selenium dioxide
Antonucci et al. Δ5, 7-Steroids. VII. The Conversion of Δ5, 7-to Δ5, 7, 9-Steroidal Hormones
Batres et al. Steroids. LXXVI. Synthesis of Long Chain Carboxylic Acid Esters of 17α-Hydroxyprogesterone
US2762818A (en) 4-hydroxytestosterone and esters thereof
Heymann et al. A New Route to 11-Ketosteroids by Fission of a▵ 9 (11)-Ethylene Oxide1, 2
Eadon et al. Mass spectrometry in structural and stereochemical problems. CCXI. Effect of structural variations on the electron impact-induced fragmentations of steroid hydrocarbons
US3299108A (en) 17alpha-alkynyl/alkenyl-13beta-alkyl-11-alkylgona-1, 3, 5 (10)-triene-3, 17beta-diols, ethers and esters thereof and intermediates thereto
US2769019A (en) 9-dehydrotestosterone and 9-dehydronortestosterone and esters thereof
Cooley et al. 812. Modified steroid hormones. Part VII. The conversion of 3-oxo-Δ 4-steroids into their 6-methyl homologues
EHRENSTEIN et al. INVESTIGATIONS ON STEROIDS. XI. NEW TRANSFORMATION PRODUCTS OF STROPHANTHIDIN: STUDIES ON ETHYL 3 (β), 5, 19-TRIHYDROXYETIOCHOLANATE1
US2875215A (en) 1-acylthio substitution products of 3, 17-dioxygenated androstane derivatives
PT87117B (en) 17-METHYL-17-METHYL-4,15-STRTRIENT-3-ONA AND NEW INTERMEDIARY PRODUCTS FOR THE PREPARATION OF 17-A-ETHINYL-17B-HYDROXY-18-METHYL-
Smith et al. Application of the Favorskii Rearrangement to the Preparation of A-Norsteroids
US2683712A (en) Steroid alkali-metal enolates
US2855404A (en) 19-oxygenated derivatives of 17a-oxa-dhomo-4-androstene-3, 17-dione
Johnson Glutarimide antibiotics. I. The synthesis of actiphenol
Adams et al. Senecio Alkaloids: α-Longilobine; Structure of α-Longinecic Acid
US2683723A (en) Steroid alkali-metal enolates