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Ravi et al., 1996 - Google Patents

Role of vagal lung C-fibres in the cardiorespiratory effects of capsaicin in monkeys

Ravi et al., 1996

Document ID
2382178129327186602
Author
Ravi K
Singh M
Publication year
Publication venue
Respiration physiology

External Links

Snippet

Apnoea, bradycardia and hypotension were elicited by right atrial injections of capsaicin in anaesthetized monkeys. At the threshold dose (2.5±0.3 μg/kg), tachypnoea was elicited (latency 1.6±0.2 s) which got replaced by apnoea with higher doses of capsaicin. These …
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K38/22—Hormones
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
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