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Tsui et al., 1982 - Google Patents

Persistence of freely replicating SV40 recombinant molecules carrying a selectable marker in permissive simian cells

Tsui et al., 1982

Document ID
2136089953240501965
Author
Tsui L
Breitman M
Siminovitch L
Buchwald M
Publication year
Publication venue
Cell

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Snippet

We have demonstrated that a SV40-pBR322 recombinant vector (pSVP-gpt) carrying a bacterial gene of selectable phenotype (Eco-gpt) may persist extrachromosomally in COSl cells, a simian cell line that endogenously produces SV40 large T antigen. The amount of …
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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