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McManus et al., 2013 - Google Patents

Turning a kinase deoxyribozyme into a sensor

McManus et al., 2013

Document ID
2058142380989275231
Author
McManus S
Li Y
Publication year
Publication venue
Journal of the American Chemical Society

External Links

Snippet

The vast majority of deoxyribozyme-based sensors are designed using modified RNA- cleaving deoxyribozymes and detect analytes that act as allosteric regulators of their catalytic activity. These sensors are susceptible to background signals due to catalytic …
Continue reading at pubs.acs.org (other versions)

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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the means of detection
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