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Dexl et al., 2018 - Google Patents

Displacement of the transcription factor B reader domain during transcription initiation

Dexl et al., 2018

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Document ID
1973699010583263518
Author
Dexl S
Reichelt R
Kraatz K
Schulz S
Grohmann D
Bartlett M
Thomm M
Publication year
Publication venue
Nucleic Acids Research

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Transcription initiation by archaeal RNA polymerase (RNAP) and eukaryotic RNAP II requires the general transcription factor (TF) B/IIB. Structural analyses of eukaryotic transcription initiation complexes locate the B-reader domain of TFIIB in close proximity to …
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1062—Isolating an individual clone by screening libraries mRNA-Display, e.g. polypeptide and encoding template are connected covalently
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
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    • G01N33/53—Immunoassay; Biospecific binding assay
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