Kim et al., 2005 - Google Patents
Ubiquitin ligase MKRN1 modulates telomere length homeostasis through a proteolysis of hTERTKim et al., 2005
View PDF- Document ID
- 1874751756507778787
- Author
- Kim J
- Park S
- Kang M
- Oh S
- Lee T
- Muller M
- Chung I
- Publication year
- Publication venue
- Genes & development
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Snippet
Telomere homeostasis is regulated by telomerase and a collection of associated proteins. Telomerase is, in turn, regulated by post-translational modifications of the rate-limiting catalytic subunit hTERT. Here we show that disruption of Hsp90 by geldanamycin promotes …
- 229920000511 telomere 0 title abstract description 29
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