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Bertrand et al., 2002 - Google Patents

Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo

Bertrand et al., 2002

Document ID
18286008953887253114
Author
Bertrand J
Pottier M
Vekris A
Opolon P
Maksimenko A
Malvy C
Publication year
Publication venue
Biochemical and biophysical research communications

External Links

Snippet

Efficiencies of a nuclease resistant antisense oligonucleotide and of siRNA both being targeted against the green fluorescent protein stably expressed in HeLa cells are compared in cell cultures and in xenografted mice. Using Cytofectin GSV to deliver both inhibitors, the …
Continue reading at www.sciencedirect.com (other versions)

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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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