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Liu et al., 2015 - Google Patents

Epigenetic silencing of HDAC1 by miR-449a upregulates Runx2 and promotes osteoblast differentiation

Liu et al., 2015

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Document ID
18097451695552936168
Author
Liu T
Hou L
Zhao Y
Huang Y
Publication year
Publication venue
International journal of molecular medicine

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Human‑induced pluripotent (iPS) cells can be induced to differentiate into osteoblasts, but the process is inefficient and time‑consuming. Previous studies indicated a close association between the expression of Runx2 and osteoblast differentiation, and established that the …
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
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