[go: up one dir, main page]

Khudyakov et al., 2002 - Google Patents

Artificial DNA: Methods and applications

Khudyakov et al., 2002

Document ID
17539056496915570414
Author
Khudyakov Y
Fields H
Publication year

External Links

Snippet

Combining elements of biochemistry, molecular biology, and immunology, artificial DNA can be employed in a number of scientific disciplines. Some of the varied applications include site-specific mutagenesis, hybridization, amplification, protein engineering, anti-sense …
Continue reading at www.taylorfrancis.com (other versions)

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • C07H19/20Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL CHEMISTRY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/06Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • C07H19/10Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1062Isolating an individual clone by screening libraries mRNA-Display, e.g. polypeptide and encoding template are connected covalently
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL CHEMISTRY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
    • C40B60/00Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14For creating libraries
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides

Similar Documents

Publication Publication Date Title
EP0375278B1 (en) Automated system for polynucleotide synthesis and purification
US5262530A (en) Automated system for polynucleotide synthesis and purification
US6001993A (en) Random oligonucleotide libraries and methods of making the same
US6586211B1 (en) Method for producing polymers
US4659774A (en) Support for solid-phase oligonucleotide synthesis
AU2006252281B2 (en) Linkers and co-coupling agents for optimization of oligonucleotide synthesis and purification on solid support
US8173368B2 (en) Programmable oligonucleotide synthesis
US5359052A (en) Chalcophospholanes useful in the synthesis of oligonucleoside phosphorothioates, phosphorodithioates and related selenates
US5175209A (en) Porous wafer for segmented synthesis of biopolymers
AU712779C (en) Method for solution phase synthesis of oligonucleotides
EP0035719B1 (en) Process for producing modified inorganic polymers, their use in producing polynucleotides, and a reagent useful in these processes
US4591614A (en) Preparation of oligodeoxyribonucleoside alkyl or arylphosphonates
JPH0643438B2 (en) A method for the simultaneous synthesis of several oligonucleotides on a solid phase.
US5324831A (en) Phosphoramidite reagent for chemical synthesis of modified DNA
AU602753B2 (en) Porous wafer for segmented synthesis of biopolymers
Beaucage et al. Synthetic strategies and parameters involved in the synthesis of oligodeoxyribonucleotides according to the phosphoramidite method
US6248877B1 (en) Solid phase synthesis of organic compounds via phosphitylating reagents
Khudyakov et al. Artificial DNA: Methods and applications
Seliger et al. An Update on Protection of 5′‐Hydroxyl Functions of Nucleosides and Oligonucleotides
Pon Chemical Synthesis of Oligonucleotides: From Dreams to Automation
CN119410752B (en) A biosynthetic method and application of oligo pool
US6153742A (en) General process for the preparation of cyclic oligonucleotides
BASES et al. THYMINE DIMERS-DNA LESIONS INDUCED BY SUNLIGHT CIS-SYN THYMINE DIMER PHOSPHORAMIDITE NOW AVAILABLE
JP3028814B2 (en) Porous wafers for split synthesis of biopolymers
Greef Synthesis and biochemical studies of phosphorodithioate RNA