[go: up one dir, main page]

Herrera-Molina et al., 2017 - Google Patents

Neuroplastin deletion in glutamatergic neurons impairs selective brain functions and calcium regulation: implication for cognitive deterioration

Herrera-Molina et al., 2017

View HTML @Full View
Document ID
16711343296980176417
Author
Herrera-Molina R
Mlinac-Jerkovic K
Ilic K
Stöber F
Vemula S
Sandoval M
Milosevic N
Simic G
Smalla K
Goldschmidt J
Bognar S
Montag D
Publication year
Publication venue
Scientific reports

External Links

Snippet

The cell adhesion molecule neuroplastin (Np) is a novel candidate to influence human intelligence. Np-deficient mice display complex cognitive deficits and reduced levels of Plasma Membrane Ca2+ ATPases (PMCAs), an essential regulator of the intracellular Ca2+ …
Continue reading at www.nature.com (HTML) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders

Similar Documents

Publication Publication Date Title
Herrera-Molina et al. Neuroplastin deletion in glutamatergic neurons impairs selective brain functions and calcium regulation: implication for cognitive deterioration
Yang et al. Presynaptic autophagy is coupled to the synaptic vesicle cycle via ATG-9
Chih et al. A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain
Yamaguchi et al. Atg9a deficiency causes axon-specific lesions including neuronal circuit dysgenesis
Devaraju et al. Haploinsufficiency of the 22q11. 2 microdeletion gene Mrpl40 disrupts short-term synaptic plasticity and working memory through dysregulation of mitochondrial calcium
Vogel-Ciernia et al. The neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory
Ittner et al. Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease
Kushibiki et al. RIMB-1/RIM-binding protein and UNC-10/RIM redundantly regulate presynaptic localization of the voltage-gated calcium channel in Caenorhabditis elegans
Gouzi et al. The receptor tyrosine kinase Alk controls neurofibromin functions in Drosophila growth and learning
Matt et al. SynDIG4/Prrt1 is required for excitatory synapse development and plasticity underlying cognitive function
Zhao et al. Amyloid beta peptides block new synapse assembly by nogo receptor-mediated inhibition of T-type calcium channels
Yamauchi et al. Netrin-1 derived from the ventricular zone, but not the floor plate, directs hindbrain commissural axons to the ventral midline
Sakuma et al. Drosophila Strip serves as a platform for early endosome organization during axon elongation
Mochizuki et al. Unc-51/ATG1 controls axonal and dendritic development via kinesin-mediated vesicle transport in the Drosophila brain
Vingtdeux et al. CALHM1 deficiency impairs cerebral neuron activity and memory flexibility in mice
Kwan et al. DIXDC1 phosphorylation and control of dendritic morphology are impaired by rare genetic variants
Lai et al. Drosophila microRNA-34 impairs axon pruning of mushroom body γ neurons by downregulating the expression of ecdysone receptor
Alqadah et al. SLO BK potassium channels couple gap junctions to inhibition of calcium signaling in olfactory neuron diversification
Willmes et al. Investigation of hippocampal synaptic transmission and plasticity in mice deficient in the actin-binding protein Drebrin
Olguin et al. KHSRP loss increases neuronal growth and synaptic transmission and alters memory consolidation through RNA stabilization
Biju et al. Deletion of voltage‐gated channel affects glomerular refinement and odorant receptor expression in the mouse olfactory system
Rigby et al. Endoplasmic reticulum acetyltransferases Atase1 and Atase2 differentially regulate reticulophagy, macroautophagy and cellular acetyl-CoA metabolism
Silvestre et al. Cell type-specific expression, regulation and compensation of CDKL5 activity in mouse brain
Nieratschker et al. Bruchpilot in ribbon-like axonal agglomerates, behavioral defects, and early death in SRPK79D kinase mutants of Drosophila
Sulkowski et al. Turtle functions downstream of Cut in differentially regulating class specific dendrite morphogenesis in Drosophila